76574-43-1

Usage

Uses

Used in Pharmaceutical Industry:
2-(2,3-Dimethylphenyl)acetonitrile is used as an intermediate in the production of pharmaceuticals for its ability to be incorporated into the synthesis of various pharmacological agents and organic compounds. Its structural properties allow for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
2-(2,3-Dimethylphenyl)acetonitrile is used as an intermediate in the production of agrochemicals, contributing to the synthesis of compounds that can be utilized in the development of pesticides, herbicides, and other agricultural chemicals to enhance crop protection and yield.
Used in Organic Synthesis:
2-(2,3-Dimethylphenyl)acetonitrile is used as a building block in the synthesis of various organic molecules, allowing for the creation of a wide range of chemical compounds with diverse applications in different industries, including the development of new materials, dyes, and other specialty chemicals.
Used in Medicinal Chemistry and Drug Discovery:
2-(2,3-Dimethylphenyl)acetonitrile has potential applications in the field of medicinal chemistry and drug discovery due to its structural versatility and synthetic utility. It can be used to explore new chemical entities and optimize the properties of existing drugs, leading to the discovery of novel therapeutic agents with improved efficacy and safety profiles.

InChI:InChI=1/C10H11N/c1-8-4-3-5-10(6-7-11)9(8)2/h3-5H,6H2,1-2H3

Upstream product

• 13651-55-3 2,3-dimethylbenzyl chloride 
• 151-50-8 potassium cyanide 
• 583-71-1 4-bromo-o-xylene 
• 75-05-8 acetonitrile 
• 99749-00-5 lithioacetonitrile 
• 13651-14-4 (2,3-dimethylphenyl)methanol 
• 1116-76-3 Tri-n-octylamine 
• 74-87-3 methylene chloride 
• 140-29-4 phenylacetonitrile 

Downstream Products

• 67685-71-6 2-(2,3-dimethylphenyl)ethan-1-amine 
• 103030-60-0 (2,3-dimethyl-phenyl)-acetic acid amide 
• 30981-98-7 2,3-dimethylphenylacetic acid 
• 727429-82-5 2-(2,3-dimethyl-phenyl)-3-methyl-butyronitrile 
• 76574-86-2 6-(2,3-Dimethyl-phenyl)-2-methyl-pyrido[2,3-d]pyrimidin-7-ylamine 
• 76574-63-5 6-(2,3-Dimethyl-phenyl)-pyrido[2,3-d]pyrimidin-7-ylamine 
• 179343-29-4 6-(2,3-dimethyl-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine 
• 6975-04-8 2-(2,3-dimethyl-phenyl)-3-methyl-butyric acid 
• 855649-27-3 5,6-dimethyl-3,4-dihydro-isoquinoline 
• 219650-77-8 (4-Methylsulfonyloxyimino-cyclohexa-2,5-dienylidene)-(3,4-dimethylphenyl)-acetonitrile 

Relevant academic research and scientific papers

Process for the alkylation of alkyl-or benzylcyanogen derivatives in the presence of trialkylamines or trialkylphosphines

A process for the alkylation of compounds of the formula II where the reaction with the alkylating agent is carried out in the presence of a base and a trialkylamine and/or trialkylphosphine.

188. Addition of Carbon Nucleophiles to Tricarbonylchromium Complexes of 1,2-Dihydrocyclobutabenzene, Indane, 1,2,3,4-Tetrahydronaphthalene and ortho-Xylene

3-Substituted 1,2-dihydrocyclobutabenzenes (bicycloocta-1,3,5-triene) are readily accessible from (1) via a two-step sequence which involves addition of a nucleophile and oxidation of the intermediate anionic

Reaction of 4-Bromo-1,2-dimethylbenzene with Various Nucleophiles via Aryne Reaction

4-Bromo-1,2-dimethylbenzene (4a) reacts with a variety of amines, mercaptans, and nitriles under aryne-forming conditions to yield predominantly 4-substituted 1,2-dimethylbenzenes and minor quantities of 3-substituted 1,2-dimethylbenzenes.The product distributions from these reactions are heavily in favor of the 4-substituted isomer since it is formed exclusively from the symmetric 4,5-dimethylbenzyne intermediate (6) and partly from the unsymmetric 3,4-dimethylbenzyne intermediate (5).

Antihypertensive Activity of 6-Arylpyridopyrimidin-7-amine Derivatives

A series of 51 6-arylpyridopyrimidin-7-amine derivatives was prepared and evaluated for antihypertensive activity in the conscious spontaneously hypertensive rat.A number of these compounds, notably 6-(2,6-dichlorophenyl)-2-methylpyridopyrimidin-7-amine (36), lowered blood pressure in these rats in a gradual and sustained manner to normotensive levels at oral doses of 10-50 mg/kg.Normalized blood pressure levels could then be maintained by single daily oral doses.The effect of structural variation in the 6-aryl group and in the 2 and 4 positions of the pyridopyrimidine ring on activity is reported and discussed.