7658-90-4Relevant academic research and scientific papers
Copper-catalyzed direct amination of polyfluoroarenes and azoles with hydroxylamines and its application to the synthesis of 3-aminobenzoheteroles
Matsuda, Naoki,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
experimental part, p. 1792 - 1797 (2012/07/28)
A copper-catalyzed electrophilic, umpolung amination strategy for the direct C-H amination of polyfluoroarenes and 1,3-azoles has been developed. The copper-based amination reaction is robust and can be easily scaled up on a gram scale. Its application to
Copper-catalyzed direct amination of electron-deficient arenes with hydroxylamines
Matsuda, Naoki,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
supporting information; experimental part, p. 2860 - 2863 (2011/07/07)
The C-H amination of electron-deficient arenes such as polyfluoroarenes and azole compounds with O-acylated hydroxylamines effectively proceeds in the presence of a copper catalyst even at room temperature to provide the corresponding anilines and aminoaz
Copper-catalyzed oxidative amination of benzoxazoles via C-H and C-N bond activation: A new strategy for using tertiary amines as nitrogen group sources
Guo, Shengmei,Qian, Bo,Xie, Yinjun,Xia, Chungu,Huang, Hanmin
supporting information; experimental part, p. 522 - 525 (2011/04/18)
An efficient and conceptually new method for oxidative amination of azoles with tertiary amines via copper-catalyzed C-H and C-N bond activation has been developed. This protocol can be performed in the absence of external base and only requires atmospheric oxygen as oxidant. The catalyst system is very simple and efficient, which opens a new way for using tertiary amines as nitrogen group sources for C-N bond formation reactions.
