765902-00-9

Upstream product

• 1191-99-7 2,3-dihydro-2H-furan 
• 29540-84-9 4-chlorophenyl trifluoromethanesulfonate 
• 108-22-5 Isopropenyl acetate 
• 91671-36-2 1-(4-chlorophenyl)buta-2,3-dien-1-ol 
• 1679-18-1 4-Chlorophenylboronic acid 

Relevant academic research and scientific papers

Preparation of a fluorous chiral BINAP and application to an asymmetric Heck reaction

Fluorous chiral BINAP ((R)-F13BINAP) was prepared and was applied to an asymmetric Heck reaction. The enantioselectivity was similar in BTF homogeneous system (90% ee) to that of the original non-fluorous reaction and marginally higher in benzene and FC-72 biphasic system (93% ee) than that of the original non-fluorous one.

C1-Symmetric Binap Derivative Featuring Single Diferrocenylphosphino-Donor Moiety

A C1-symmetric chiral bisphosphine, FcPh-Binap (1), which possesses a single diferrocenylphosphino moiety together with a conventional Ph2P-substituent, was prepared in enantiomerically pure forms. Ligand 1 is sterically less demanding than Fc-Segphos (A)

Enzyme- and Ruthenium-Catalyzed Enantioselective Transformation of α-Allenic Alcohols into 2,3-Dihydrofurans

An efficient one-pot method for the enzyme- and ruthenium-catalyzed enantioselective transformation of α-allenic alcohols into 2,3-dihydrofurans has been developed. The method involves an enzymatic kinetic resolution and a subsequent ruthenium-catalyzed c

Enantio- and regioselective heck-type reaction of arylboronic acids with 2,3-dihydrofuran

(Figure Presented) Reported herein is a protocol for the enantioselective Pd(II)-catalyzed Heck-type reaction between arylboronic acids and 2,3-dihydrofuran. The highest chemical and optical yields were obtained when a Pd(OAc)2/(R)-MeO(bipheny

Enantioselective carbon-carbon bond forming reactions using fluorous chiral catalysts

Fluorous chiral BINOLs and BINAP were prepared and used as the ligands for an asymmetric addition of Et2Zn to aromatic aldehydes and an asymmetric Heck reaction, respectively. The enantioselectivities were similar in homogeneous system to those of the original non-fluorous reactions. Consecutive reactions were examined by utilizing fluorous-organic biphase and fluorous solid phase extraction techniques. Enantioselectivities in consecutive reactions were close to that attained in the non-fluorous system. The solid phase extraction method also enabled us to perform a simultaneous screening procedure.

Chiral fluorous phosphorus ligands based on the binaphthyl skeleton: Synthesis and applications in asymmetric catalysis

Two enantiopure fluorous phosphines have been conveniently synthesized by combining palladium-catalyzed coupling reactions of easily available binaphthyl building-blocks with the introduction of fluorous ponytails onto aromatic compounds via ether bond fo

Regio- and enantio-selective Heck reactions of aryl and alkenyl triflates with the new chiral ligand (R)-BITIANP

The Heck reaction of dihydrofuran 3 with aryl triflates 4 and 6a-d and alkenyl triflate 8 in the presence of the chiral ligand (R)-BITIANP 1 provides the 2-substituted 2,3-dihydrofurans 5a, 7a-d and 9, respectively, with complete regioselectivity, high en

Palladium-catalyzed asymmetric arylation of 2,3-dihydrofuran: 1,8-Bis(dimethylamino)naphthalene as an efficient base

Reaction of 2,3-dihydrofuran with aryl triflate (1) in the presence of a base and a palladium catalyst, generated in situ from Pd(OAc)2 and (R)-BINAP, gave (R)-2-aryl-2,3-dihydrofuran (2) and a small amount of (S)-2-aryl-2,5-dihydrofuran (3). T