76645-84-6Relevant academic research and scientific papers
OPTISCH AKTIVE N-PHOSPHINOMETHYLIERTE α-AMINOSAEUREN: SYNTHESE UND ANWENDUNG ALS LIGANDEN IN ASYMMETRISCHEN HYDRIERUNGEN MIT RHODIUM-KOMPLEXEN
Kellner, K.,Tzschach, A.,Nagy-Magos, A.,Marko, L.
, p. 307 - 314 (1980)
α-Aminoacids, their esters and sodium salts may be transformed by a modified Mannich-reaction into N-phosphinomethyl or N,N-bis(phosphinomethyl) derivatives.The sodium or triethylammonium salts of the chiral bisphosphines L-(-)-N,N-bis(diphenylphosphinomethyl)-alanine and -valine may be used as ligands to form enantioslective hydrogenation catalysts with rhodium complexes.The highest optical yield achieved was 29percent.
