766557-61-3

Usage

Uses

Used in Pharmaceutical Industry:
2-Isopropoxy-3-iodo-pyridine is used as an intermediate in the synthesis of various pharmaceuticals for its unique structural properties that can be incorporated into drug molecules to enhance their therapeutic effects.
Used in Agricultural Products:
In the agricultural sector, 2-Isopropoxy-3-iodo-pyridine serves as an intermediate in the production of agrochemicals, contributing to the development of effective and targeted pest control solutions.
Used in Organic Synthesis:
2-Isopropoxy-3-iodo-pyridine is utilized as a building block in the preparation of various organic compounds, thanks to its distinctive pyridine ring and functional groups that can be further modified or reacted in organic synthesis processes.
Used in Chemical Research:
2-ISOPROPOXY-3-IODO-PYRIDINE is employed in chemical research as a model or probe molecule to study reaction mechanisms, explore new synthetic routes, and develop innovative methodologies in organic chemistry.

InChI:InChI=1/C8H10INO/c1-6(2)11-8-7(9)4-3-5-10-8/h3-6H,1-2H3

Upstream product

• 113975-22-7 2-fluoro-3-iodopyridine 
• 67-63-0 isopropyl alcohol 

Relevant academic research and scientific papers

Copper-catalyzed trifluoromethylation of alkoxypyridine derivatives

The trifluoromethylation of aromatic and heteroaromatic cores has attracted considerable interest in recent years due to its pharmacological relevance. We studied the extension of a simple copper-catalyzed trifluoromethylation protocol to alkoxy-substituted iodopyridines and their benzologs. The trifluoromethylation proceeded smoothly in all cases, and the desired compounds were isolated and characterized. In the trifluoromethylation of 3-iodo-4-methoxyquinoline, we observed a concomitant O-N methyl migration, resulting in the trifluoromethylated quinolone as a product. Overall, the described procedure should facilitate the broader use of copper-catalyzed trifluoromethylation in medicinal chemistry.

BIARYL DERIVATIVE AS GPR120 AGONIST

The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a GPR120 agonist, promoting GLP-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory activity in the macrophage, pancreatic cells and the like, and allowing effective use in prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

BIARYL DERIVATIVES AS GPR120 AGONISTS

The present invention relates to biaryl derivatives of Formula 1, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof. The biaryl derivatives of Formula 1 according to the present invention promote GLP-1 formation in the gastrointestinal tract and improve insulin resistance in the liver or in muscle due to anti-inflammatory action in macrophages, lipocytes, etc., and can accordingly be effectively used for preventing or treating diabetes, complications of diabetes, obesity, non-alcoholic fatty liver, steatohepatitis, osteoporosis or inflammation.