767265-77-0

Usage

Uses

Used in Pharmaceutical Industry:
4-Piperidinecarboxylicacid, 4-hydroxy-, methylester (9CI) is used as an intermediate in the synthesis of various drugs. Its unique chemical properties make it a valuable component in the development of new pharmaceutical compounds.
Used in Medicinal Chemistry and Drug Discovery:
Due to its potential applications in the synthesis of drugs, 4-Piperidinecarboxylicacid, 4-hydroxy-, methylester (9CI) is utilized in the field of medicinal chemistry and drug discovery. Researchers leverage its properties to explore and develop novel pharmaceutical compounds with potential therapeutic benefits.

Upstream product

• 3612-20-2 1-phenylmethyl-4-piperidone 
• 67-56-1 methanol 
• 59119-18-5 1-benzyl-4-hydroxypiperidine-4-carboxylic acid 
• 6094-60-6 1-benzyl-4-hydroxypiperidine-4-carbonitrile 
• 60437-30-1 4-hydroxy-4-(methoxycarbonyl)-1-(phenylmethyl)piperidine 

Downstream Products

• 1192189-86-8 1-tert-butyl 4-methyl 4-(benzyloxy)piperidine-1,4-dicarboxylate 
• 1192189-90-4 3-[4-hydroxy-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamido]phenyl N,N-dimethylcarbamate 
• 1192189-85-7 3-[4-benzyloxy-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamido]phenyl N,N-dimethylcarbamate 
• 1192189-89-1 3-[4-(benzyloxy)piperidine-4-carboxamido]phenyl N,N-dimethylcarbamate hydrochloride 
• 1192189-88-0 tert-butyl 4-(benzyloxy)-4-[3-(N,N-dimethylcarbamoyloxy)phenylcarbamoyl]piperidine-1-carboxylate 
• 1192189-87-9 4-benzyloxy-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid 
• 1300609-06-6 2-(4-hydroxy-4-(hydroxymethyl)piperidin-1-yl)-4-(4-methoxy-3-(trifluoromethyl)phenylamino)pyrido[4,3-d]pyrimidin-5(6H)-one 

Relevant academic research and scientific papers

PHENOTHIAZINE DERIVATIVES AND USES THEREOF

The present invention provides phenothiazine compounds, processes for their preparation, pharmaceutical compositions comprising the compounds, and the use of the compounds or the compositions in the treatment of various diseases or conditions, for example ribosomal disorders and ribosomopathies, e.g. Diamond Blackfan anemia (DBA).

COMPOUNDS USEFUL AS IMMUNOMODULATORS

The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.

Anesthetic compounds and related methods of use

Provided herein are compounds according to formula (I): Provided herein is also a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.

IMIDAZOLE DERIVATIVES

Described herein are compounds of formula I. The compounds of formula I act as DGAT1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for hyperlipidemia, diabetes mellitus and obesity.

ANTIBACTERIAL COMPOUNDS

The present invention provides a compound of the following formula and salts thereof: Also provided is the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.

BIPHENYL SUBSTITUTED SPIROTETRONIC ACIDS AND THEIR USE FOR THE TREATMENT OF RETROVIRAL DISEASES

The present invention relates to novel substituted spirotetronic acids (I) in which R1 and R2, together with the carbon atom to which they are bonded, form a group of the formula (1), (2), (3) or (4), whereby * represents the carbon

Novel amides useful for treating pain

The present invention relates to compounds of formula (I) that useful in treating pain.

Novel amides useful for treating pain

The present invention relates to compounds of formula (I-VII) or a pharmaceutically acceptable salt or prodrug thereof, in which A, L, R6, R7 and R8 are defined herein. The present invention also relates to methods of trating pain using these compounds and pharmaceutical compositions including these compounds.