7675-01-6

Basic information

• Product Name: 3-(thiophen-2-ylsulfanyl)propanoic acid
• CAS NO: 7675-01-6
• Molecular Formula: C₇H₈O₂S₂
• Molecular Weight: 188.2672
• Mol File: 7675-01-6.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 354.4°C at 760 mmHg
• Flash Point: 168.1°C
• Density: 1.36g/cm³
• Vapor Pressure: 1.23E-05mmHg at 25°C
• Refractive Index: 1.618
• CAS DataBase Reference: 3-(thiophen-2-ylsulfanyl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(thiophen-2-ylsulfanyl)propanoic acid(7675-01-6)
• EPA Substance Registry System: 3-(thiophen-2-ylsulfanyl)propanoic acid(7675-01-6)

Safety Data

• Hazardous Substances Data: 7675-01-6(Hazardous Substances Data)

Upstream product

• 7774-74-5 Thiophene-2-thiol 
• 590-92-1 3-Bromopropionic acid 
• 79-10-7 acrylic acid 
• 188290-36-0 thiophene 

Downstream Products

• 7675-04-9 5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-one 
• 1432445-18-5 3-(thiophen-2-ylthio)-1-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)propan-1-one 

Relevant articles and documents

Design, synthesis and biological evaluation of 1,4-dihydrothieno[3′, 2′:5,6]thiopyrano[4,3-c]pyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists

The estrogen receptor is a target for therapeutic agents for hormone replacement in menopausal women, osteoporosis, reproductive cancers such as breast cancer, uterine cancer and prostate cancer. 1,4-Dihydrothieno[3′, 2′:5,6]thiopyrano[4,3-c]pyrazole-3-ca

Trimethylamine and application of trimethylamine

The invention belongs to the field of medicine technology, and relates to a trimethylamine and apreparation method thereof and an application as the epidermal growth factor receptor tyrosine kinase inhibitor. The compounds, a prodrugs of the compounds, a pharmaceutically active metabolites and the pharmaceutically acceptable salts have the structure of formula (I) : R may be independently selectedfrom the group consisting of hydrogen, C1-C6 alkyl; R', R'' are independently selected from the group consisting of hydrogen, C1-C6 alkyl, substituted or unsubstituted phenyl, wherein the substituentis C1-C4 alkyl, C1-C4 alkoxy, halogen, halogenated C1-C4 alkyl, halogenated C1-C4 alkoxy, substituted or unsubstituted C1-C6 alkyl, wherein the substituent is dimethylamino, morpholinyl, methoxyphenoxy, methoxyphenyl; R', and R'', together with a nitrogen atom to which they are attached, form a morpholinyl or a cycloaliphatic radical. The formula is shown in the formula.

Thiophenothiazolacyl piperazine compound and medical use thereof

The invention belongs to the technical field of medicines, and relates to a thiophenothiazolacyl piperazine compound and a preparation method thereof as well as application of the thiophenothiazolacylpiperazine compound as an epidermal growth factor receptor tyrosine kinase inhibitor. The compound, a precursor drug thereof, an active metabolite of the drug and pharmaceutically acceptable salt are as shown in the formula (I), wherein R is independently selected from hydrogen and methyl; R' is independently selected from hydrogen, C1-C4 alkyl, C1-C4 alkoxy, hydroxyl, cyan, halogen, amino, nitryl, trifluoromethyl or trifluoromethoxy.