768357-96-6Relevant academic research and scientific papers
BENZODICYCLOALKANE DERIVATIVE, PREPARATION METHOD AND USE THEREOF
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Paragraph 0154; 0172; 0173, (2019/06/19)
It is provided herein a benzobicycloalkane derivative, and a preparation method and use thereof. In particular, it is provided herein a compound of Formula (I), or a pharmaceutically acceptable salt, stereoisomer or solvate thereof, a preparation method, and a use thereof in preparation of drugs for treating pain.
A novel series of urea-based peptidomimetic calpain inhibitors
Sanders, M. Lee,Donkor, Isaac O.
, p. 1965 - 1968 (2007/10/03)
A series of peptide aldehyde derivatives in which the P2 chiral carbon has been replaced with nitrogen were synthesized as urea-based peptidomimetic inhibitors of μ-calpain. The compounds mirrored the general SAR of peptidyl aldehyde calpain inhibitors but displayed greater selectivity for μ-calpain over cathepsin B.
