768404-05-3Relevant academic research and scientific papers
Synthesis and preliminary biological evaluation of radiolabeled 5-BDBD analogs as new candidate PET radioligands for P2X4 receptor
Wang, Min,Gao, Mingzhang,Meyer, Jill A.,Peters, Jonathan S.,Zarrinmayeh, Hamideh,Territo, Paul R.,Hutchins, Gary D.,Zheng, Qi-Huang
, p. 3835 - 3844 (2017/06/13)
P2X4 receptor has become an interesting molecular target for treatment and PET imaging of neuroinflammation and associated brain diseases such as Alzheimer's disease. This study reports the first design, synthesis, radiolabeling and biological evaluation
BENZOFURO-1,4-DIAZEPIN-2-ONE DERIVATIVES
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Page/Page column 10; 14, (2008/06/13)
The invention relates to novel benzofuro-1,4-diazepin-2-one derivatives, to a method for producing said derivatives and to their use as P2X4 receptor antagonists for producing medicaments for the treatment and/or prophylaxis of diseases, in par
