76844-97-8

Upstream product

• 3899-65-8 1-chloro-4,5-dimethoxy-2-nitrobenzene 
• 14005-14-2 2,2-dimethyl-1,3-benzodioxole 
• 61588-38-3 5-chloro-2,2-dimethyl-6-nitro-benzo[1,3]dioxole 

Downstream Products

• 99360-06-2 1,2-diethoxy-4-chloro-5-nitro-benzene 
• 120589-08-4 1-benzyloxy-4-chloro-2-hydroxy-5-nitrobenzene 
• 120589-09-5 1,2-Bis-benzyloxy-4-chloro-5-nitro-benzene 
• 120589-18-6 6-amino-7-phenoxy-2,3-dihydro-1,4-benzodioxin-2-ylmethanol 
• 120589-25-5 6-nitro-7-phenoxy-2,3-dihydro-1,4-benzodioxin-2-ylmethanol 
• 76845-02-8 7-phenoxy-6-sulfamoyl-2,3-dihydro-1,4-benzodioxin-2-ylmethanol 
• 76845-25-5 7-phenoxy-6-sulfamoyl-2,3-dihydro-1,4-benzodioxin-2-carboxylic acid 
• 76849-68-8 2-chloromethyl-7-phenoxy-6-sulfamoyl-2,3-dihydro-1,4-benzodioxin 
• 76845-20-0 7-Chloro-6-sulfamoyl-2,3-dihydro-benzo[1,4]dioxine-2-carboxylic acid (2,6-dimethyl-phenyl)-amide 
• 76845-17-5 2-(4-Benzyl-piperazin-1-ylmethyl)-7-chloro-2,3-dihydro-benzo[1,4]dioxine-6-sulfonic acid amide 
• 98488-04-1 4-ethoxy-6-nitro-resorcinol 
• 102871-29-4 4-ethoxy-5-methoxy-2-nitro-phenol 
• 55403-58-2 1-nitro-2,4,5-triethoxybenzene 
• 1073437-09-8 5-chloro-2-(2,3-difluoro-6-methoxybenzyloxy)-4-nitrophenol 

Relevant academic research and scientific papers

NITROGENATED FUSED RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE OF THE SAME FOR MEDICAL PURPOSES

[Purpose] The present invention provides compounds useful as agents for the prevention or treatment of a sex hormone-dependent disease or the like. [Solution] The present invention provides nitrogen-containing fused ring derivatives represented by the following general formula (I) which has a GnRH antagonistic activity, prodrugs, salts, pharmaceutical compositions containing the same, medicinal uses thereof and the like. In the formula (I), rings A and B are independently aryl or heteroaryl; RA and RB are independently halogen, cyano, alkyl, alkylsulfonyl, -OW1, -SW1, -COW2, -NW3W4, -SO2NW3W4, aryl, etc.; RC is H or alkyl; E is oxygen atom, etc.; U is single bond or alkylene; and X is Y, -CO-Y, -SO2-Y -S-(alkylene)-Y, -O-(alkylene)-Y, -SO2-(alkylene)-Y, etc.; Y is Z or amino, etc.; and Z is cycloalkyl, heterocycloalkyl, aryl, heteroaryl, etc.