76859-49-9

Upstream product

• 62853-46-7 5-deoxy-3-O-methyl-1,2-O-(methylethylidene)-α-D-xylo-hexo-furanose 
• 76859-47-7 (3R,4S)-4-[(2S,3R)-3-(Ethylsulfanyl-methylsulfanyl-methyl)-5-methoxy-tetrahydro-furan-2-yl]-4-methoxy-butane-1,3-diol 
• 76859-44-4 (E)-3-[(4S,5S,6R)-5-Methoxy-6-(2-methoxymethoxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-acrylic acid methyl ester 
• 76859-45-5 (R)-4-Methanesulfinyl-3-[(4S,5S,6R)-5-methoxy-6-(2-methoxymethoxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-4-methylsulfanyl-butyric acid methyl ester 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 26487-92-3 3-(triphenylphosphoranylidene)butan-2-one 
• 76859-48-8 (2S,3R)-2-((1S,2R)-2,4-Bis-benzyloxy-1-methoxy-butyl)-5-methoxy-tetrahydro-furan-3-carbaldehyde 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF CARBOMYCIN B AND JOSAMYCIN (LEUCOMYCIN A3)

The stereospecific total synthesis of macrolide antibiotics, carbomycin B and josamycin (leucomycin A3), is described.The key aglycone has been synthesized by coupling two segments of C1-C10 and C11-C16 portions, which are stereospecifically de