TOTAL SYNTHESIS OF CARBOMYCIN B AND JOSAMYCIN (LEUCOMYCIN A3)

DOI: 10.1016/S0040-4039(00)78621-7

Source and publish data:

Tetrahedron Letters p. 2837 - 2840 (1980)

Update date:2022-08-02

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Authors:

Tatsuta, Kuniaki

Amemiya, Yoshiya

Maniwa, Shunji

Kinoshita, Mitsuhiro

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Article abstract of DOI:10.1016/S0040-4039(00)78621-7

The stereospecific total synthesis of macrolide antibiotics, carbomycin B and josamycin (leucomycin A₃), is described.The key aglycone has been synthesized by coupling two segments of C1-C10 and C11-C16 portions, which are stereospecifically de

Full text of DOI:10.1016/S0040-4039(00)78621-7

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