7687-79-8 Usage
Description
1,3-Dichloro-5,6-dihydro-4H-cyclopenta[c]thiophen-4-one is a cyclic organochlorine compound with the molecular formula C8H6Cl2OS. It features a thiophene ring structure and is recognized for its potential biological activities, including anti-inflammatory and anti-cancer properties. This chemical compound is also valued as a versatile building block in the synthesis of pharmaceutical and agrochemical products, as well as a reagent in organic synthesis for preparing other organic compounds.
Uses
Used in Pharmaceutical Industry:
1,3-Dichloro-5,6-dihydro-4H-cyclopenta[c]thiophen-4-one is used as a building block for the synthesis of various pharmaceutical products due to its potential biological activities and chemical versatility.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, 1,3-Dichloro-5,6-dihydro-4H-cyclopenta[c]thiophen-4-one serves as a key intermediate in the development of agrochemical products, contributing to its effectiveness and applicability in this field.
Used in Organic Synthesis:
1,3-Dichloro-5,6-dihydro-4H-cyclopenta[c]thiophen-4-one is used as a reagent in organic synthesis for the preparation of other organic compounds, highlighting its utility in creating a wide range of chemical entities.
Used in Research and Development:
1,3-Dichloro-5,6-dihydro-4H-cyclopenta[c]thiophen-4-one is also utilized in research and development settings for studying its potential as an anti-inflammatory and anti-cancer agent, given its noted biological activities and the ongoing quest for novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 7687-79-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,8 and 7 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7687-79:
(6*7)+(5*6)+(4*8)+(3*7)+(2*7)+(1*9)=148
148 % 10 = 8
So 7687-79-8 is a valid CAS Registry Number.
7687-79-8Relevant articles and documents
CONDENSED THIOPHENE DERIVATIVES AS HYPOXIA INDUCIBLE FACTOR (HIF) INHIBITORS
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, (2021/06/04)
Compounds of the formula I in which R1, R2, R3, R4, R5, n and m have the meanings indicated in Claim 1, are inhibitors of HIF-2α, and can be employed for the treatment of diseases such as cancer.
Pyridylfuran and pyridylthiophene compounds
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, (2008/06/13)
A compound of the formula: and its pharmaceutically effective salts, wherein R1 and R2 are independently selected from the following: (a) hydrogen, halo, R5-, C2-6 alkenyl, C2-6 alkynyl, hydroxy-R5-, R5-O-R5-, or the like; (b) Ar-, Ar-R5-, Ar-C2-6 alkenyl, Ar-C2-6 alkynyl, Ar-O-, Ar-O-R5- or the like; (c) R5-C(O)-, -NO2, cyano, NH2-C(O)-, R5-NH-C(O)-, (R5)2-N-C(O)-, Ar-C(O)- or the like; and (d) R5-C(O)-NH-, Ar-C(O)-NH- or the like; wherein Ar is optionally substituted aryl or heteroaryl such as phenyl and pyridyl; and wherein R5 is optionally halo-substituted C1-6 alkyl; R3 is selected from the following: (e) cyano, formyl, tetrazolyl, triazolyl, imidazolyl, oxazolyl, thiazolyl, R5-C(O)-, C2-6 alkenyl-C(O)-, C2-6 alkynyl-C(O)-, R5-C(O)-R5-, or the like; (f) R5-C(O)-NH-, Ar-C(O)-NH-, or the like; (g) R5-S-, R5-S(O)-, R5-NH-S(O)2-, or the like; and (h) Ar-C(O)-, Ar-R5-C(O)-, Ar-C2-6 alkenylene-C(O)- or the like; or two of R1, R2 and R3 together form a group of the formula -A1-B1-A2- or -A1-B1-A3-B2-A2- such as cyclic alkyl optionally substituted with oxo; R4 is hydrogen, halo, R5-C(O)- and the like; X is O, S, S(O) or S(O)2; m is 0, 1, 2, 3 or 4. The present invention also provides processes for the preparation thereof, the use thereof in treating cytokine mediated diseases and/or cell adhesion molecule (CAM) mediated diseases and pharmaceutical compositions for use in such therapy.
