769140-90-1 Usage
General Description
The chemical (R)-2-(1-hydroxy-2-chloroethyl)-pyridine is a type of pyridine compound that contains a hydroxy group, a chloroethyl group, and a pyridine ring. (R)-2-(1-hydroxy-2-chloroethyl)-pyridine is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It can also be used as a building block in chemical reactions to create more complex molecules. This chemical has potential applications in drug development and medicinal chemistry due to its structural properties and reactivity. However, as with any chemical compound, careful handling and safety precautions should be taken when working with (R)-2-(1-hydroxy-2-chloroethyl)-pyridine to ensure the safety of individuals and the surrounding environment.
Check Digit Verification of cas no
The CAS Registry Mumber 769140-90-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,9,1,4 and 0 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 769140-90:
(8*7)+(7*6)+(6*9)+(5*1)+(4*4)+(3*0)+(2*9)+(1*0)=191
191 % 10 = 1
So 769140-90-1 is a valid CAS Registry Number.
769140-90-1Relevant articles and documents
The synthesis of two potent β-3 adrenergic receptor agonists
Bradley, Paul A.,Lecouturier, Yann C.,Noeureuil, Pierre,Patel, Bhairavi,Wheeler, Simon,Carroll, Robert J.,Moore, Robert,Snow, Jonathan
, p. 1326 - 1336 (2011/09/20)
This contribution describes the initial preparation of two potent β-3 receptor agonists 1 and 2. Subsequent scale up of these two compounds was required for further evaluation and proceeded via a common key amine intermediate 24. Synthesis of this key intermediate by way of a Ritter reaction was a vital step in the sequence. Enantioselective Noyori hydrogenation reactions gave access to the chiral epoxides necessary to make the target compounds. Chemistry was developed for the selective dehalogenation of the 2-chloropyridyl group in the presence of a sensitive isoxazole unit to provide access to 1.
PROCESS TO PRODUCE ENANTIOMERICALLY ENRICHED 1-ARYL- AND 1-HETEROARYL-2-AMINOETHANOLS
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Page 12-13, (2008/06/13)
The invention relates to a method of preparing enantiomerically enriched amino alcohols of Formula (I) wherein the variable R1, R2, and R3 are defined herein.
