76973-35-8

Usage

InChI:InChI=1/C20H15ClN4O/c1-12-17-18(13-7-9-14(21)10-8-13)16(11-22)19(23)26-20(17)25(24-12)15-5-3-2-4-6-15/h2-10,18H,23H2,1H3/t18-/m1/s1

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 89-25-8 edaravone 
• 109-77-3 malononitrile 
• 82805-64-9 2-[(4-Chloro-phenyl)-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-methyl]-malononitrile 
• 1867-38-5 4-chlorobenzylidenemalonodinitrile 
• 71289-10-6 4-(4-chlorobenzylidene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one 
• 141-97-9 ethyl acetoacetate 
• 100-63-0 phenylhydrazine 
• 942-32-5 5-methyl-2-phenyl-2H-pyrazol-3-ol 
• 39143-10-7 (Z)-4-(4-chlorobenzylidene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one 

Downstream Products

• 173438-73-8 4-(4-Chloro-phenyl)-5-imino-3-methyl-1-phenyl-1,4-dihydro-5H-9-oxa-1,2,6,8-tetraaza-cyclopenta[b]naphthalen-6-ylamine 
• 223389-87-5 4-(4-chlorophenyl)-3,7-dimethyl-1-phenyl-4,6-dihydropyrazolo[4',3':5,6]pyrano[2,3-d]pyrimidine-5(1H)-one 
• 1375261-88-3 4-(4-chlorophenyl)-3-methyl-1-phenyl-4,6-dihydropyrazolo[4',3':5,6]pyrano[2, 3-d] pyrimidin-5(1H)-one 
• 1444154-50-0 3-methyl-4-(4-chlorophenyl)-1-phenyl-4,8-dihydropyrazolo[4’,3’:5,6]-pyrano[2,3-d]pyrimidine-5,7(1H,6H)-dithione 
• 1444154-69-1 N-[4-(4-chlorophenyl)-3-methyl-1-phenyl-7-thioxo-1,4,7,8-tetrahydro-pyrazolo[4’,3’:5,6]pyrano[2,3-d]pyrimidine-5-yl]thiourea 
• 1444154-59-9 4-(4-chlorophenyl)-5-imino-3-methyl-1,6-diphenyl-4,5,6,8-tetrahydro-pyrazolo[4’,3’:5,6]pyrano[2,3-d]pyrimidine-7(1H)-thione 
• 1334596-75-6 5-amino-4-(4-chlorophenyl)-3-methyl-1-phenyl-4,8-dihydro-2(H)-pyrazolo[4',3':5,6]pyrano[2,3-d]pyrimidine-7(1H)-one 
• 1334596-85-8 5-amino-4-(4-chlorophenyl)-3-methyl-1-phenyl-4,8-dihydro-2(H)-pyrazolo[4',3':5,6]pyrano[2,3-d]pyrimidine-7(1H)-thione 
• 173438-67-0 N-[4-(4-Chloro-phenyl)-5-cyano-3-methyl-1-phenyl-1,4-dihydro-pyrano[2,3-c]pyrazol-6-yl]-formimidic acid ethyl ester 

Relevant academic research and scientific papers

Sugarcane Bagasse Ash-Based Silica-Supported Boric Acid (SBA-SiO2-H3BO3): A Versatile and Reusable Catalyst for the Synthesis of 1,4Dihydropyrano[2,3c]pyrazole Derivatives

Abstract: A simple, green, and efficient protocol has been developed for the synthesis of biologically active 1,4dihydropyrano[2,3c]pyrazole derivatives via one-pot four-component reaction of various substituted benzaldehydes, hydrazine hydrate or phenylh

Zn (II)-Schiff base covalently anchored to CaO@SiO2: A hybrid nanocatalyst for green synthesis of 4H-pyrans

In this study, the Zn (II)-Schiff base covalently anchored onto the surface of CaO@SiO2 nanoparticles. The structure of this hybrid nanomaterial (CaO@SiO2-NH2-Sal-Zn) was characterized using the analytical techniques such

Catalyst-free UV365-assisted synthesis of pyran annulated heterocyclic scaffolds and evaluation of their antibacterial activities

A convenient and eco-friendly, one-pot synthetic protocol for pharmaceutically important pyran-based heterocyclic compounds is repeated herein. The reactions were carried out at room temperature in a water–ethanol solvent mixture under direct irradiation

Synthesis and characterization of Fe3O4@THAM-SO3H as a highly reusable nanocatalyst and its application for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives

In this work, a new, green and beneficial nanomagnetic catalyst was easily fabricated using sulfuric acid as an acidic group on Fe3O4 nanoparticles coated with tris (hydroxymethyl) aminomethane (THAM). The synthesized catalyst was characterized by FT-IR, TGA/DTG, XRD, TEM, EDS, VSM, and SEM analyses. Next, its catalytic activity was studied for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives. This catalyst has advantages such as high catalytic activity, non-toxicity, easy separation from the reaction mixture using an external magnet and reuses for several times without significantly reducing in its catalytic activity.

Sulfonic acid-functionalized Fe3O4-supported magnetized graphene oxide quantum dots: A novel organic-inorganic nanocomposite as an efficient and recyclable nanocatalyst for the synthesis of dihydropyrano[2,3-c]pyrazole and 4H-chromen

In this research, the main emphasis has been focused on the preparation of a novel Fe3O4-supported propane-1-sulfonic acid-grafted graphene oxide quantum dots (Fe3O4@GOQD-O-(propane-1-sulfonic acid)) that it was

An Eco-friendly Catalytic System for One-pot Multicomponent Synthesis of Diverse and Densely Functionalized Pyranopyrazole and Benzochromene Derivatives

An external base-free, efficient, cost-effective, and environmentally benign protocol has been developed for the one-pot multicomponent synthesis of highly functionalized pyranopyrazoles and benzochromenes using water extract of Agave americana (century p

Application of Yttrium Iron Garnet as a Powerful and Recyclable Nanocatalyst for One-Pot Synthesis of Pyrano[2,3-c]pyrazole Derivatives under Solvent-Free Conditions

The application of yttrium iron garnet (YIG) superparamagnetic nanoparticles as a new recyclable and highly efficient heterogeneous magnetic catalyst for one-pot synthesis of pyrano[2,3-c]pyrazole derivatives under solvent-free conditions, as well as etherification and esterification reactions are described. The advantages of the proposed method include the lack of organic solvents, clean reaction, rapid removal of the catalyst, short reaction times, excellent yields, and recyclability of the catalyst.

Fe3O4-supported N-pyridin-4-amine-grafted graphene oxide as efficient and magnetically separable novel nanocatalyst for green synthesis of 4H-chromenes and dihydropyrano[2,3-c]pyrazole derivatives in water

Abstract: Fe3O4-magnetized N-pyridin-4-amine-functionalized graphene oxide [Fe3O4@GO-N-(pyridin-4-amine)] was readily prepared via a three-step procedure. The synthesized nanofilms were characterized by scanning

Environmentally benign synthesis of pyranopyrazole derivatives by cobalt Schiff-base complexes immobilized on magnetic iron oxide nanoparticles

In this work, an efficient and straight procedure has been described for one-pot three-component synthesis of pyranopyrazole derivatives in the presence of a new cobalt Schiff-base complex immobilized on silica-coated Fe3O4 nanoparti

A concise route for the one-pot multi-component synthesis of 4,6-disubstituted 2-aminopyridine-3-carbonitriles and pyranopyrazoles using cobalt (II) nitrate hexahydrate as catalyst

Three facile and efficient routes for one-pot, cobalt (II) nitrate hexahydrate catalyzed multi-component synthesis of 2-amino-3-cyanopyridine and pyranopyrazole derivatives have been developed. The present protocols offer the products in good yields from the simple and readily available starting materials. The other salient features of these protocols are operational simplicity, easy isolation of product without the need of column chromatographic purification, and the use of cobalt (II) nitrate hexahydrate as an efficient catalyst.