76988-37-9Relevant academic research and scientific papers
2-Benzazepines. 7. Synthesis of pyrimido[5,4-d][2]benzazepines [1]
Earley,Fryer,Gilman
, p. 1195 - 1197 (2007/10/02)
Two novel syntheses of pyrimido[5,4-d][2]benzazepines are described. The first synthesis stared with 3-phenylphthalide which in three steps was converted to a functionalized pyrimidine which was cyclized to give the 2-benzazepine ring system. The second a
2-Benzazepines. 5. Synthesis of pyrimido[5,4-d][2]benzazepines and their evaluation as anxiolytic agents
Trybulski, Eugene J.,Benjamin, Louis E.,Earley, James V.,Fryer, R. Ian,Gilman, Norman W.,et al.
, p. 1589 - 1596 (2007/10/02)
A series of 5H-pyrimido[5,4-d][2]benzazepines has been synthesized, starting from the corresponding 2-benzazepine-5-ones, and evaluated as potential anxiolytic agents. Selected compounds from this series show a pharmacological profile of action different
