769933-15-5 Usage
Molecular Structure
The compound has a complex molecular structure, which includes a thienoimidazole ring fused to a pentanamide group.
Hexahydro-2-oxo group
The compound contains a hexahydro-2-oxo group, which is a six-carbon ring with two hydrogens attached to the second carbon and a ketone group (C=O) on the third carbon.
4-Aminophenyl side chain
The compound has a 4-aminoethyl side chain, which is an amino group (-NH2) attached to a phenyl ring (a six-carbon ring with alternating single and double bonds).
Amino group in the side chain
The 4-aminophenyl side chain contains an amino group, which can form hydrogen bonds and participate in various chemical reactions.
Stereochemistry
The stereochemistry of the compound is specified as (3aS,4S,6aR), indicating the spatial arrangement of the atoms in the molecule. This is important for understanding the compound's interactions with biological targets and its potential pharmacological activity.
Biological and pharmacological activity
The compound's structure suggests that it could interact with biological targets or have physiological effects. However, further research is needed to determine the specific properties and potential applications of this compound.
Hexahydro
The compound is hexahydro, meaning it contains six hydrogen atoms in its structure. This can affect its solubility, stability, and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 769933-15-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,9,9,3 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 769933-15:
(8*7)+(7*6)+(6*9)+(5*9)+(4*3)+(3*3)+(2*1)+(1*5)=225
225 % 10 = 5
So 769933-15-5 is a valid CAS Registry Number.
769933-15-5Relevant articles and documents
Expanding APEX2 Substrates for Proximity-Dependent Labeling of Nucleic Acids and Proteins in Living Cells
Zhou, Ying,Wang, Gang,Wang, Pengchong,Li, Zeyao,Yue, Tieqiang,Wang, Jianbin,Zou, Peng
, p. 11763 - 11767 (2019/08/08)
The subcellular organization of biomolecules such as proteins and nucleic acids is intimately linked to their biological functions. APEX2, an engineered ascorbate peroxidase that enables proximity-dependent labeling of proteins in living cells, has emerged as a powerful tool for deciphering the molecular architecture of various subcellular structures. However, only phenolic compounds have thus far been employed as APEX2 substrates, and the resulting phenoxyl radicals preferentially react with electron-rich amino acid residues. This narrow scope of substrates could potentially limit the application of APEX2. In this study, we screened a panel of aromatic compounds and identified biotin-conjugated arylamines as novel probes with significantly higher reactivity towards nucleic acids. As a demonstration of the spatial specificity and depth of coverage in mammalian cells, we applied APEX2 labeling with biotin-aniline (Btn-An) in the mitochondrial matrix, capturing all 13 mitochondrial messenger RNAs and none of the cytoplasmic RNAs. APEX2-mediated Btn-An labeling of RNA is thus a promising method for mapping the subcellular transcriptome, which could shed light on its functions in cell physiology.
