769957-36-0Relevant academic research and scientific papers
E-ring modified steroids as novel potent inhibitors of 17β- hydroxysteroid dehydrogenase type 1
Fischer, Delphine S.,Allan, Gillian M.,Bubert, Christian,Vicker, Nigel,Smith, Andrew,Tutill, Helena J.,Purohit, Atul,Wood, Lynn,Packham, Graham,Mahon, Mary F.,Reed, Michael J.,Potter, Barry V. L.
, p. 5749 - 5770 (2007/10/03)
17β-Hydroxysteroid dehydrogenases (17β-HSDs) are an important class of steroidogenic enzymes that regulate the bioavailability of active estrogens and androgens and are as yet a relatively unexploited therapeutic target. Based on our investigations and th
