770-86-5Relevant academic research and scientific papers
Phenyliodine(III) Diacetate/I2-Mediated Domino Approach for Pyrrolo[1,4]Thiazines and 1,4-Thiazines by a One-Pot Morin Rearrangement of N,S-Acetals
Danton, Fanny,Othman, Mohamed,Lawson, Ata Martin,Moncol, Ján,Ghinet, Alina,Rigo, Beno?t,Da?ch, Adam
, p. 6113 - 6118 (2019/04/17)
An efficient domino transformation using a phenyliodine(III) diacetate (PIDA)/I2 combination towards Morin 1,4-thiazine compounds has been developed starting from N,S-acetals. The latter leads to “one-step” regioselective methylene insertion without the need for traditional sulfoxide intermediates in good yields. The reaction involves easily accessible N,S-acetals obtained from cost-effective basic ketones and cysteamine as starting materials. This process ultimately leads to 1,4-thiazines related to natural product and fused derivatives necessary for further QSAR study.
Comparative radioprotective activity of various pentagonal compounds with two heteroatomes
Robbe,Fernandez,Dubief,et al.
, p. 235 - 243 (2007/10/02)
Various heterocyclic compounds with two heteroatomes were synthesized and their potential radioprotective activity was tested. This study shows the interest of phenylthiazolidines derivatives in chemical radioprotection.
2-Phenyl thiazolidine derivatives as radioprotective agents
Terol,Fernandez,Robbe,et al.
, p. 149 - 151 (2007/10/04)
31 derivatives of 2-phenyl thiazolidine were submitted to radio-pharmacological tests on mice. They usually present little toxicity and some of them show a rather interesting activity.
