133913-49-2

Basic information

• Product Name: 1-phenyl-3-thiazolidin-3-yl-propan-1-one
• Synonyms: 1-phenyl-3-thiazolidin-3-yl-propan-1-one
• CAS NO: 133913-49-2
• Molecular Weight: 221.323
• Mol File: 133913-49-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-phenyl-3-thiazolidin-3-yl-propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-3-thiazolidin-3-yl-propan-1-one(133913-49-2)
• EPA Substance Registry System: 1-phenyl-3-thiazolidin-3-yl-propan-1-one(133913-49-2)

Safety Data

• Hazardous Substances Data: 133913-49-2(Hazardous Substances Data)

Upstream product

• 2682-49-7 thiazolidine-2-one 
• 936-59-4 3-chloropropiophenone 
• 14446-47-0 thiazolidine hydrochloride 
• 98-86-2 acetophenone 
• 50-00-0 formaldehyd 
• 770-86-5 2-methyl-2-phenylthiazolidine 
• 19351-18-9 2,2-dimethyl-1,3-thiazolidine 
• 504-78-9 1,3-thiazolidine 

Relevant articles and documents

Heterocyclic compounds containing nitrogen and sulfur, pharmaceutical compositions containing them and process for preparing same

The invention relates to novel nitrogen- and sulfur-containing heterocyclic compounds of the formula (I), acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the formula (I) STR1 Ar stands for an optionally mono- or polysubstituted aryl or heteroaryl group; R1 means a carbonyl or (C2-6 alkenyl)carbonyl group; R2 stands for hydrogen C1-6 alkyl, phenyl or phenyl (C1-4 alkyl) group; R3 means hydrogen or (C1-6 alkoxy)carbonyl group; R4 and R5 stand, independently from each other, for hydrogen or C1-6 alkyl group; R6 ogen, C1-6 alkyl group or halophenyl group; m is 0 or 1; and n is 1 or 2, with the proviso that R2 means hydrogen when m is 0. The compounds of formula (I) show a significant cerebral antihypoxic action and thus, they can be used for the treatment of diseases caused by hypoxic brain damages such as e.g. the senile dementia, Alzheimer's disease or disturbances of the cognitive function.