77049-30-0Relevant academic research and scientific papers
One-pot synthesis of spiro pyrroloimidazoles and 2-arylimidazoles from 1,2-diaza-1,3-butadienes and arylamidines
Attanasi, Orazio A.,Giorgi, Gianluca,Favi, Gianfranco,Filippone, Paolino,Lillini, Samuele,Perrulli, Francesca R.,Santeusanio, Stefania
, p. 1691 - 1694 (2007)
1,2-Diaza-1,3-butadienes react as Michael acceptors with nitrogen 1,3-dinucleophiles, such as arylamidines, in a one-pot heterocyclization reaction. Depending on the nature of the acyl residue at the terminal carbon of the heterodiene system, spiro pyrrol
Synthesis of 1H-Imidazoles by the Simple Ring Transformation of 5-Acylaminouracils and 5-Acylaminopyrimidin-4(3H)-ones
Matsuura, Izumi,Ueda, Taisei,Murakami, Nobutoshi,Nagai, Shin-ichi,Sakakibara, Jinsaku
, p. 2821 - 2826 (2007/10/02)
1,2-Disubstituted 4-alkylcarbamoyl-5-methyl-1H-imidazoles and 2-substituted 5-methyl-4-phenylcarbamoyl-1H-imidazoles were synthesized from 5-acylamino-6-methyluracils and 5-acylamino-6-methyl-3-phenylpyrimidin-4(3H)-ones by treatment with sodium hydroxide in ethanol.In the case of 5-acylaminopyrimidinones which possess an olefinic group in the acylamino group, 2-ethoxyethyl (or 2-ethoxypropyl)-5-methyl-4-phenylcarbamoyl-1H-imidazoles were prepared as major products and the corresponding 2-alkenyl-1H-imidazoles were only minor products.Compounds which contain an aryl function in their acylamino group gave glycine anilides as byproducts.
