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Guanidine, N-[3-(4-Methyl-1-piperazinyl)phenyl]-, also known as GMP, is a chemical compound with potential therapeutic properties used in the pharmaceutical industry. It is a guanidino compound featuring a piperazine ring and a phenyl group, indicating possible biological activity. GMP's unique structure and potential pharmacological effects make it a promising candidate for research and development in medicine and drug discovery.

770671-04-0

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770671-04-0 Usage

Uses

Used in Pharmaceutical Industry:
Guanidine, N-[3-(4-Methyl-1-piperazinyl)phenyl]is used as a pharmaceutical compound for its potential applications in treating various medical conditions. Its structure and properties suggest it may be effective in addressing central nervous system disorders and cancer, making it a valuable asset for further research and development in medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 770671-04-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,0,6,7 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 770671-04:
(8*7)+(7*7)+(6*0)+(5*6)+(4*7)+(3*1)+(2*0)+(1*4)=170
170 % 10 = 0
So 770671-04-0 is a valid CAS Registry Number.

770671-04-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[3-(4-methylpiperazin-1-yl)phenyl]guanidine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:770671-04-0 SDS

770671-04-0Relevant articles and documents

Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents

Shao, Hao,Shi, Shenhua,Foley, David W.,Lam, Frankie,Abbas, Abdullah Y.,Liu, Xiangrui,Huang, Shiliang,Jiang, Xiangrui,Baharin, Nadiah,Fischer, Peter M.,Wang, Shudong

, p. 447 - 455 (2013/11/19)

A series of 2,4,5-trisubstituted pyrimidines have been synthesised and characterised, which exhibited potent CDK inhibition and anti-proliferative activities. The structure-activity relationship is analysed and a rational for CDK9 selectivity is discussed

PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USE AS JANUS KINASE MODULATORS

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Page/Page column 103, (2009/05/28)

Provided herein are pyrrolopyrimidine compounds of Formula (I) wherein R1 is a heteroaryl containing at least one S atom, and optionally substituted on a ring carbon by one, two, or three substituents each independently selected from the group consisting of : halo, hydroxyl, nitro, formyl, formamido, cyano, sulfonyl, carboxy, amino, amido, acylamino, carbamoyl, sulphamoyl, alkyl, alkenyl, CF3, ureido, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, carbaldehyde oxime, N -alkylsulphamoyl, N-alkylcarbamoyl, -OR13R11 or -R13R11; R2 is phenyl or pyridinyl, wherein R2 optionally substituted on a ring carbon by one, two, or three substituents each indenpendently selected from the group consisting of : halo, hydroxyl, cyano, nitro, formyl, formamido, carboxy, sulfonyl, amino, amido, -N- alkyl -amino, carbamoyl, sulphamoyl, CF3, ureido, alkyl, alkenyl, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, N-alkylsulphamoyl, N-alkylcarbamoyl, -OR11, -OR12R11, or -R12R11; and methods of making and using the same. Such compounds may be used in inflammatory or myeloproliferative disorders. The disclosure also provides for treating cancer.

PYRAZOLO-QUINAZOLINE DERIVATIVES,PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS

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Page 195, (2008/06/13)

Pyrazolo-quinazoline derivatives of formula (Ia) or (Ib) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.

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