77103-90-3

Usage

Uses

Used in Pharmaceutical Industry:
1-(1,2,3,4-tetrahydro-1-hydroxy-1-naphthalenyl)is used as a potential compound for the development of new drugs in the pharmaceutical industry. Its unique molecular structure, which includes a naphthalenyl group, may offer novel therapeutic properties that can be harnessed for the treatment of various medical conditions.
Used in Dye Industry:
In the dye industry, 1-(1,2,3,4-tetrahydro-1-hydroxy-1-naphthalenyl)may be utilized as a component in the synthesis of new dyes or pigments. 1-(1,2,3,4-tetrahydro-1-hydroxy-1-naphthalenyl)-'s aromatic nature could contribute to the development of dyes with unique color characteristics and improved performance properties.
Used in Other Industrial Applications:
Beyond the pharmaceutical and dye industries, 1-(1,2,3,4-tetrahydro-1-hydroxy-1-naphthalenyl)may also find use in other industrial applications. Its specific properties and potential applications in these areas will depend on the results of further research and testing, which will help to elucidate the compound's full range of capabilities and potential benefits.

Upstream product

• 82720-23-8 2-ethynyl-1,2,3,4-tetrahydronaphthalen-2-ol 
• 7677-24-9 trimethylsilyl cyanide 
• 676-58-4 methylmagnesium chloride 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 

Downstream Products

• 67106-36-9 1-(1,2,3,4-tetrahydronaphthalen-4-yl)ethanone 

Relevant academic research and scientific papers

Electroreductive acylation of aromatic ketones with acylimidazoles

The intermolecular reductive coupling of aromatic ketones with acylimidazoles was effected by electroreduction in the presence of chlorotrimethylsilane and gave α-trimethylsiloxy ketones and esters. The best result was obtained using Bu4NPF6 as a supporting electrolyte and a Pb cathode in THF. The α-trimethylsiloxy-containing products were transformed to the corresponding α-hydroxy ketones and esters by treatment with TBAF in THF. This method was also effective for the intramolecular reductive coupling of δ- and ε-keto acylimidazoles.

Studies on Simplified Ergoline Derivatives. A General Six-Step Synthesis of Phenyl-Substituted 4-Methyl-3,4,4a,5,6,10b-hexahydrobenzoquinolin-1-(2H)-one Analogs (1)

This communication outlines the development of a novel, general synthetic route to substituted α-tetralones 5, their subsequent conversion to the α,β-unsaturated ketones 11, and an improved, one-step transformation of 11 to the tricyclic title compounds 1.Thus, substituted derivatives of 1 can be prepared in six steps from simple benzaldehydes, or, in three steps from more readily available α-tetralones.

Hypolipidemic 4,5-Dihydro-4-oxo-5,5-disubstituted-2-furancarboxylic Acids

A series of novel 4,5-dihydro-4-oxo-5,5-disubstituted-2-furancarboxylic acids was synthesized and shown to possess potent hypotriglyceridemic activity in normal rats.In contrast to clofibrate, none of the present compounds altered liver weight at any dose