7711-52-6Relevant articles and documents
Design, synthesis and evaluation of 2-phenyl-1H-benzo[d]imidazole-4,7-diones as vascular smooth muscle cell proliferation inhibitors
Ryu, Chung-Kyu,Lee, Ra-Young,Lee, Seung-Yon,Chung, Hwa-Jin,Lee, Sang Kook,Chung, Kwang-Hoe
, p. 2948 - 2951 (2008/12/22)
A series of 2-phenyl-1H-benzo[d]imidazole-4,7-diones were synthesized and tested for their inhibitory activity on the PDGF-stimulated proliferation of rat aortic vascular smooth muscle cells. Among the tested compounds, 6-arylthio-5-chloro-2-phenyl-1H-benzo[d]imidazole-4,7-diones exhibited an potent antiproliferative activity.
Substituted benzimidazoles and benzothidiazoles having anti-asthmatic and/or anti-inflammatory activities
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, (2008/06/13)
This disclosure describes novel substituted 2-phenyl-1H-benzimidazoles and 2-phenyl-1H-benzimidazole-4,7-diones and novel 5-chloro-6-(4-substituted-1-piperazinyl)-2,1,3-benzothiadiazole-4,7-diones; all of which are highly active as anti-asthmatic and anti