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α-(Triazolopyridin-7-yl)-4-methoxybenzyl alcohol is a complex organic compound with the molecular formula C16H14N2O3. It features a benzyl alcohol core, which is a benzene ring with a hydroxyl group attached to a carbon atom, and a methoxy group (-OCH3) at the para position. The molecule also contains a triazolopyridine moiety, which is a fused ring system consisting of a pyridine ring (a six-membered nitrogen-containing aromatic ring) and a triazole ring (a five-membered ring with three nitrogen atoms). This chemical structure is of interest in medicinal chemistry and drug design due to its potential to interact with various biological targets, such as enzymes and receptors, which can lead to the development of new therapeutic agents. The specific arrangement of the triazolopyridine and benzyl alcohol groups can influence the compound's pharmacological properties, making it a subject of study for its potential applications in the field of pharmaceuticals.

77134-20-4

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77134-20-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 77134-20-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,1,3 and 4 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77134-20:
(7*7)+(6*7)+(5*1)+(4*3)+(3*4)+(2*2)+(1*0)=124
124 % 10 = 4
So 77134-20-4 is a valid CAS Registry Number.

77134-20-4Relevant academic research and scientific papers

Triazolopyridines. 16. Lithiation of 3-Cianotriazolo-pyridine

Jones, Gurnos,Mouat, Deborah J.,Pitman, Mark A.,Lunt, Edward,Lythgoe, David J.

, p. 10969 - 10978 (1995)

Various methods for the synthesis of 3-cyanotriazolopyridine 8 by diazo transfer to 2-pyridylacetonitrile are described.Lithiation of the triazolopyridine 8 using LDA or TMPA followed by quenching with TMS chloride, gave the 4-mono-, the 7-mono-, and the

Triazolopyridines. Part 2. Preparation of 7-Substituted Triazolopyridines by Directed Lithiation

Jones, Gurnos,Sliskovic, D. Robert

, p. 967 - 972 (2007/10/02)

The lithiation reactions of 1,2,3-triazolopyridine (1) to give the 7-lithio-derivative (4; R = Li), and of its 7-methyl derivative (16) to give the 7-lithiomethyl compound, are described.These lithium derivatives react with electrophiles, notably a

[1,2,3]Triazolo[1,5-a]pyridine - a synthon for 6-substituted pyridine-2-carboxaldehydes

Jones, Gurnos,Sliskovic, D.Robert

, p. 4529 - 4530 (2007/10/02)

[1,2,3]Triazolo[1,5-a]pyridine (1) is lithiated in position 7; the lithio derivative is used to synthesize triazolopyridinyl alcohols (6) which can be converted into 6-substituted pyridine-2-aldehydes (3).

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