77134-74-8 Usage
Uses
Used in Organic Synthesis:
[4-(HYDROXYMETHYL)-1-TRITYL-1H-IMIDAZOL-5-YL]METHANOL is used as a protecting group in organic synthesis for temporarily masking reactive functional groups, facilitating the synthesis of complex organic molecules.
Used in Pharmaceutical Development:
In the pharmaceutical industry, [4-(HYDROXYMETHYL)-1-TRITYL-1H-IMIDAZOL-5-YL]METHANOL is used as a key intermediate in the synthesis of new drug candidates, owing to its unique structural features and potential for chemical modification.
Used in Specialty Chemicals:
[4-(HYDROXYMETHYL)-1-TRITYL-1H-IMIDAZOL-5-YL]METHANOL is utilized in the development of specialty chemicals, where its unique properties can be harnessed for specific applications, such as in the creation of advanced materials or chemical sensors.
Check Digit Verification of cas no
The CAS Registry Mumber 77134-74-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,1,3 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 77134-74:
(7*7)+(6*7)+(5*1)+(4*3)+(3*4)+(2*7)+(1*4)=138
138 % 10 = 8
So 77134-74-8 is a valid CAS Registry Number.
InChI:InChI=1/C24H22N2O2/c27-16-22-23(17-28)26(18-25-22)24(19-10-4-1-5-11-19,20-12-6-2-7-13-20)21-14-8-3-9-15-21/h1-15,18,27-28H,16-17H2
77134-74-8Relevant academic research and scientific papers
Synthesis and antiproliferatory activity of ruthenium complexes containing N-heterocyclic carboxylates
Kennedy, David C.,James, Brian R.
, p. 32 - 36 (2017/03/11)
Solvates of the complexes Ru2Cl(pic)4(EtOH) (2), Ru(Im-CO2)3 (3), and Ru(Im-CO2)(Im-CO2H)Cl2 (4), were synthesized from reaction of RuCl3·3H2O or K3[RuCl6] with the N-heterocyclic carboxylic acids pyridine-2-carboxylic acid (picolinic acid, Hpic), and imidazole-4-carboxylic acid (Im-CO2H). Crystals of 2–4 could not be grown and hence characterization was done by elemental analysis, NMR, IR, and conductivity data; 2 and 4 were tested for antiproliferatory activity in vitro against a human breast cancer cell line, but were less active than, for example, Ru complexes containing bis-imidazole or 4,4′-biimidazole that we studied previously [see Can. J. Chem. 89 (2011) 948]. Preliminary work with a third potential ligand, 3-nitro-1,2,4-triazole-5-carboxylic acid (abbreviated HCANT), and other nitro heterocyclic compounds is also presented.
