77149-39-4

Upstream product

• 100-39-0 benzyl bromide 
• 77149-38-3 1,9-dimethyl-1,9,17-triaza<2.2.2>metacyclophane-2,10,18-trione 
• 77221-04-6 3-benzoic acid 
• 77149-36-1 methyl 3-benzoate 
• 77149-35-0 methyl 3-<(N-methyl-3-nitrobenzamido)-3-benzamido>benzoate 
• 77149-37-2 3-benzoic acid 
• 77149-32-7 3-(N-methyl-3-nitrobenzamido)benzoic acid 
• 77149-33-8 3-[Methyl-(3-nitro-benzoyl)-amino]-benzoyl chloride 

Relevant academic research and scientific papers

Conformational Behaviour of Medium-sized Rings. Part 15. 1,9,17-Triazametacyclophane-2,10,18-trione Derivatives

The stepwise synthesis of 1,9-dimethyl-1,9,17-triazametacyclophane-2,10,18-trione (1) from methyl m-aminobenzoate and m-nitrobenzoyl chloride is reported.The temperature dependences (i) of the 1H-decoupled 13C n.m.r. spectrum of the 1,9,17-trimethyl derivative (2) and (ii) of the 1H n.m.r. spectrum of the 1,9-dimethyl-17-benzyl derivative (3) are interpreted in terms of equilibration between diastereoisomeric crown and saddle conformations in solution.The 1,9-dimethyl derivative (1) is believed to exist predominantly in the saddle conformation in solution.

Synthesis and conformational behaviour of 1,9,17-triaza[2.2.2]metacyclophane-2, 10, 18-trione derivatives

The 1,9,17-triaza[2.2.2]metacyclophane-2, 10, 18-trione derivatives (1) - (3) have been synthesised. X-Ray crystallography shows that the 1,9,17-trimethyl derivative (3) adopts a Crown conformation (11) in the solid state. Dynamic n.m.r. spectroscopy indi