77156-16-2

Usage

Uses

Used in Pharmaceutical Industry:
Alangimarine is used as a pharmaceutical compound for its potential therapeutic applications. The expression is: Alangimarine is used as a pharmaceutical compound for its potential therapeutic applications due to its unique chemical properties and structural characteristics.
Used in Chemical Research:
Alangimarine is also used in chemical research as a subject of study for its unique ultraviolet spectrum and acetylation properties. The expression is: Alangimarine is used as a research subject for its unique ultraviolet spectrum and acetylation properties, contributing to the understanding of its chemical behavior and potential applications in various fields.

InChI:InChI=1/C19H16N2O3/c1-3-11-9-20-10-15-13(11)7-16-14-8-17(22)18(24-2)6-12(14)4-5-21(16)19(15)23/h3,6-10,22H,1,4-5H2,2H3

Upstream product

• 109431-06-3 (+/-)-alangimaridine 
• 97168-61-1 dihydroalamarine 
• 96422-50-3 alangimarinone 
• 109355-94-4 2-benzyloxy-12-ethenyl-5,6,13,14-tetrahydro-3-methoxy-8H-isoquino<2,1-b><2,7>naphthyridin-8-one 
• 109355-93-3 2-benzyloxy-12-ethenyl-5,6,13,14-tetrahydro-3-methoxy-8H-isoquino<2,1-b><2,7>naphthyridin-8-imine 
• 15357-92-3 6-methoxy-7-(benzyloxy)-3,4-dihydroisoquinoline 
• 57110-40-4 5-ethenyl-4-methyl-3-pyridinecarbonitrile 
• 34482-51-4 alangiside 
• 77156-18-4 alamarine 
• 77173-59-2 alangimaridine 

Relevant academic research and scientific papers

Novel benzopyridoquinolizine bases from alangium lamarckii Thw.

Alangimarine (1), alamarine (2) and alangimaridine (3), isolated from the seeds of the title plant, have been characterised as a new class of alkaloids. Presence of isoalamarine (13) in the stem-bark is indicated.

Isolation of two unusual tetrahydroisoquinoline-monoterpene glucosides from alangium lamarckii as possible intermediates in the non-enzymatic formation of alangimarine from alangiside

From the fruits of Alangium lamarckii, two new glucosides (3) and (4), which possessed unusual structures different from any known tetrahydroisoquinoline-monoterpene glucosides, have been isolated. Their structures were determined on the basis of spectroscopic and chemical methods. These same glucosides were also obtained by storage of alangiside (2) in MeOH for a prolonged period and glucoside (4) was further converted to alangimarine (1), a benzopyridoquinolizine alkaloid from this plant, by the usual treatment for isolation of alkaloids, suggesting the possibility of non-enzymatic formation of alangimarine (I) from alangiside (2) via the isolated glucosides (3) and (4).

8H-Isoquinonaphthydrin-8-ones: synthesis of the Alangium alkaloids, alangimaridine and alangimarine

It is shown that 3,4-dihydroisoquinolines are activated toward nucleophilic attack by reaction with trimethylsilyl trifluoromethanesulfonate.The complex so formed reacts readily with the lithio derivative of 3-cyano-4-methyl-5-vinylpyridine, affording in

Activated Imines as Carbon Electrophiles: Applications in Alkaloid Synthesis

3,4-Dihydroisoquinolines and 3,4-dihydro-β-carbolines react with trimethylsilyl trifluoromethanesulphonate to form complexes that react readily with the lithio derivatives of 3-cyano-4-methylpyridines; the method has been applied to the synthesis of the Alangium alkaloids, (+/-)-alangimaridine and alangimarine.

Studies on Indian Medicinal Plants: Part LXXX - Benzopyridoquinolizine Alkaloids of Alangium lamarckii Thw.

Eight novel benzopyridoquinolizine alkaloids, namely, alangimarine (1), alamarine (2), alangimaridine (3), isoalangimarine (4), isoalamarine (5), alangimarinone (6), dihydroalamarine (7) and dihydroisoalamarine (8) have been isolated from the seeds of Alangium lamarckii Thw.Their structures have been established from spectroscopic data and chemical correlation.