15357-92-3

Usage

Uses

Used in Pharmaceutical Research:
7-Benzyloxy-6-methoxy-3,4-dihydro-isoquinoline is used as a building block in the synthesis of various organic compounds for pharmaceutical research. Its unique structure and properties make it a promising candidate for the development of new drugs.
Used in Organic Synthesis:
In the field of organic synthesis, 7-Benzyloxy-6-methoxy-3,4-dihydro-isoquinoline is used as a key intermediate for the preparation of a wide range of organic compounds. Its versatility and reactivity contribute to the synthesis of various target molecules.
Used in Drug Development:
7-Benzyloxy-6-methoxy-3,4-dihydro-isoquinoline is used as a potential candidate for drug development. Its pharmacological properties are under investigation, and it may offer new therapeutic opportunities in the future.
Used in Chemical Research:
In chemical research, 7-Benzyloxy-6-methoxy-3,4-dihydro-isoquinoline is used to study the properties and reactions of heterocyclic compounds. Its unique structure provides insights into the behavior of isoquinoline derivatives and their potential applications in various fields.

Upstream product

• 55803-41-3 N-formyl-2-[3-methoxy-4-(benzyloxy)phenyl]ethylamine 
• 22231-61-4 2-[4-(benzyloxy)-3-methoxyphenyl]ethylamine 
• 15357-95-6 7-(benzyloxy)-6-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 63909-38-6 1-(benzyloxy)-2-methoxy-4-[(E)-2-nitroethenyl]benzene 
• 21473-46-1 2-(4'-benzyloxy-3'-methoxyphenyl)-1-nitroethane 
• 76-05-1 trifluoroacetic acid 
• 1860-56-6 4-benzyloxy-3-methoxy-β-nitrostyrene 
• 121-33-5 vanillin 
• 100-39-0 benzyl bromide 
• 63909-38-6 3-methoxy-4-benzyloxy-ω-nitrostyrolene 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 

Downstream Products

• 52336-73-9 7-(benzyloxy)-6-methoxy-2-methyl-3,4-dihydroisoquinolinium iodide 
• 110128-36-4 2-Benzyloxy-3-methoxy-5,6,13,13a-tetrahydro-isoquino[3,2-a]isoquinolin-8-one 
• 57256-43-6 2-benzoyl-7-benzyloxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile 
• 863643-93-0 4-(2-benzoyl-7-benzyloxy-1-cyano-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-ylmethyl)-5-ethylnicotinic acid ethyl ester 
• 863643-94-1 4-(2-benzoyl-7-benzyloxy-1-cyano-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-ylmethyl)-5-vinylnicotinic acid ethyl ester 
• 1426260-25-4 C₂₀H₂₅NO₂ 
• 1426260-26-5 8-(2,4-dimethoxyphenyl)-6-methoxy-2-propyl-1,2,3,4-tetrahydroisoquinolin-7-ol 
• 1610926-30-1 3-isobutyl-9-methoxy-10-benzyloxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2-ol 
• 1610926-29-8 3-isobutyl-9-methoxy-10-benzyloxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2-one 
• 436-05-5 (±)-curine 
• 104669-18-3 Acetic acid (12S,12aR)-2-benzyloxy-3-methoxy-7-oxo-5,7,12,12a-tetrahydro-6H-6a,9-diaza-benzo[a]anthracen-12-yl ester 
• 104669-20-7 11-benzyloxy-10-methoxy-7,8-dihydro-5H-benzopyrido<3,4-g>quinolizin-5-one 

Relevant academic research and scientific papers

A Modular Access to (±)-Tubocurine and (±)-Curine - Formal Total Synthesis of Tubocurarine

Two consecutive Cu-catalyzed Ullmann-type C-O couplings permitted the first successful entry toward the curare alkaloids (±)-tubocurine and (±)-curine. Starting from vanillin, the synthetic sequence comprises 15 linear steps and includes a total of 24 transformations. In addition, the total synthesis of tubocurine represents a formal total synthesis of the famous arrow poison alkaloid tubocurarine.

Synthetic approaches to pallimamine and analogues using direct imine acylation

The use of Direct Imine Acylation (DIA) methodology for the total synthesis of pallimamine is described, with three different synthetic routes examined. The construction of three advanced δ-lactam precursors, all utilising DIA, is described, along with attempts to progress these compounds further, using three distinct desymmetrisation strategies, two involving alcohol-aryl coupling, and a third involving an unusual diastereoselective lactonisation.

Synthesis and biological evaluation of 10-11C- dihydrotetrabenazine as a vesicular monoamine transporter 2 radioligand

In this study, we synthesized a new carbon-11-labeled radiotracer, 10- 11C-dihydrotetrabenazine (10-11C-DTBZ), and evaluated its potential as a vesicular monoamine transporter 2 (VMAT2) radioligand. The radiolabeled precursor 10-O-de

8-Phenylisoquinolines And Pharmaceutical Composition Used In Treatment For Sepsis

A compound is provided. The compound includes a formula of:

Formal synthesis of the bisbenzylisoquinoline alkaloid berbamunine by asymmetric substitution of chiral organolithium compounds

Asymmetric alkylation of enantiomeric tetrahydroisoquinolyl oxazolines was achieved with 96-97% diastereoselectivity. Removal of the oxazoline chiral auxiliary and further transformations provide a straightforward synthesis of the two synthetic intermediates that were previously synthesized by resolution, and which comprise a formal synthesis of berbamunine by Ullman coupling. ARKAT-USA, Inc.

Protoberberines from Reissert- compounds. Part IX [1]. An alternative approach to dibenzoquinolizine- and isoquinonaphthyridin-13a-carboxylic acids, a novel synthesis of alangimarine

3,4-Dihydroisoquinoline-Reissert-compounds were alkylated to 1-benzyl- and 1-picolyl-derivatives, which in turn could selectively be hydrolized yielding various carboxylic acids, among others certain amino acids related to 3′,4′-deoxynorlaudanosoline carboxylic acid (DNLCA). These on treating with ethanolic KOH underwent cyclization to dibenzoquinolizine- and isoquinonaphthyridine-13a-carboxylic acids. Alternatively this cyclization also could be achieved by a more convenient one-pot procedure starting from the same dihydro-Reissert-compounds. Thermal decarboxylation afforded among others the alangia alkaloids alangimarine and dihydroalangimarine. Springer-Verlag 2004.

Aza analogues of protoberberine and phtalideisoquinoline alkaloids

Anions derived from furopyridin-3(1H)-one, by treatment with lithium diisopropylamide, react with substituted, 3,4-dihydroisoquinolines and 2-methyl-3,4-dihydroisoquinolinium salts yielding nitrogen analogues of protoberberine and phtalideisoquinoline alkaloids, respectively.