77179-43-2

Basic information

• Product Name: 1-(4-phenylpiperidino)cyclohexanecarbonitrile
• CAS NO: 77179-43-2
• Molecular Weight: 268.402
• Mol File: 77179-43-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-phenylpiperidino)cyclohexanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-phenylpiperidino)cyclohexanecarbonitrile(77179-43-2)
• EPA Substance Registry System: 1-(4-phenylpiperidino)cyclohexanecarbonitrile(77179-43-2)

Safety Data

• Hazardous Substances Data: 77179-43-2(Hazardous Substances Data)

Upstream product

• 771-99-3 4-phenylpiperidine 
• 931-97-5 1-hydroxy-1-cyclohexanecarbonitrile 

Downstream Products

• 77179-41-0 1-(1-phenylcyclohexyl)-4-phenylpiperidine 

Relevant articles and documents

New Analgesic Drugs Derived from Phencyclidine

Several esters of 1-(1-phenylcyclohexyl)-4-piperidinol (3), 1-(1-phenylcyclohexyl)-4-phenyl-4-piperidinol (10) and its propionate (11), and 1-(1-phenylcyclohexyl)-4-phenylpiperidine (13) were prepared and characterized.The new compounds, which are derived from phencyclidine, exerted analgesic activity in mice.The most potent is 10, which is twice as active as morphine.The antinociceptive activity of 10, 11, and 13 could be well correlated with their potency in the mouse vas deferens bioassay, and both were completely reversed by naloxone.