77196-49-7

Upstream product

• 77196-48-6 4,5-Dioxo-1-p-tolyl-cyclopentane-1,3-dicarboxylic acid diethyl ester 
• 77183-95-0 2-p-toluenesulfonyloxy-2-cyclopentenone 
• 6293-68-1 bis(4-methylphenyl)iodonium bromide 
• 10088-87-6 4,5-dioxo-cyclopentane-1,3-dicarboxylic acid diethyl ester 
• 3008-40-0 cyclopentane-1,2-dione 
• 77183-96-1 2-hydroxy-3-p-tolyl-2-cyclopentenone 
• 74-88-4 methyl iodide 

Downstream Products

• 343779-02-2 2,5-dimethyl-2-p-tolyl-2-cyclopentanone 
• 74285-43-1 5-methyl-2-p-tolyl-2-cyclopentenone 
• 77183-98-3 2,5-dimethyl-2-p-tolyl-2-cyclopentenone 
• 77183-97-2 2-methyl-5-p-tolyl-2-cyclopentenone 

Relevant academic research and scientific papers

Synthesis of 2-Hydroxy-3-p-tolyl-2-cyclopentenone and Its Application to Isolaurene

2-Hydroxy-3-p-tolyl-2-cyclopentenone (7), a potential starting material for synthesis of isolaurene (1), was prepared by photolysis of 2-p-toluenesulfonyloxy-2-cyclopentenone (6).Conversion of 7 into 2,5-dimethyl-2-p-tolyl-cyclopentanone (14) was carried out as follows.Methylation of 7 with methyl iodide gave 2-methoxy-3-p-tolyl-2-cyclopentanone (9), and the treatment of (9) with methyl magnesium iodide afforded 2-methyl-5-p-tolyl-2-cyclopentenone (11).This compound was allowed to react with methyl iodide in the presence of sodium methoxide to yield 2,5-dimethyl-2-p-tolyl-4-cyclopentenone (13), the hydrogenation of which over palladium charcoal gave 14.