77199-00-9Relevant academic research and scientific papers
Synthesis, pharmacological profile and docking studies of new sulfonamides designed as phosphodiesterase-4 inhibitors
Da Costa Nunes, Isabelle Karine,De Souza, Everton Tenório,Cardozo, Suzana Vanessa S.,De Frias Carvalho, Vinicius,Romeiro, Nelilma Correia,Rodrigues E Silva, Patrícia Machado,Martins, Marco Aurélio,Barreiro, Eliezer J.,Lima, Lídia Moreira
, (2016/10/26)
Prior investigations showed that increased levels of cyclic AMP down-regulate lung inflammatory changes, stimulating the interest in phosphodiesterase (PDE)4 as therapeutic target. Here, we described the synthesis, pharmacological profile and docking prop
Design, synthesis and antimalarial activity of benzene and isoquinoline sulfonamide derivatives
Kumar Parai, Maloy,Panda, Gautam,Srivastava, Kumkum,Kumar Puri, Sunil
, p. 776 - 781 (2008/09/18)
A new series of benzene and isoquinoline sulfonamide derivatives were synthesized by nucleophilic displacement reaction on benzene and isoquinoline sulfonyl chlorides by substituted amines (primary and secondary). The title compounds were evaluated for an
NOVEL CONDENSING AGENTS FOR BISCHLER-NAPIERALSKI TYPE CYCLODEHYDRATION
Nagubandi, Sreeramulu,Fodor, G.
, p. 165 - 177 (2007/10/02)
Trifluoroacetic anhydride and trifluoromethyl sulfonyl anhydride are used in Bischler-Napieralski type cyclization.Starting from the appropriate amides, the dihydroisoquinolines are formed in excellent yields.
