772-03-2

Basic information

• Product Name: 2-VINYLQUINOLINE
• Synonyms: 2-Ethenylquinoline;2-Vinylquinoline, stabilized,99%;NSC 99356;2-VINYLQUINOLINE;2-ethenyl-quinolin;2-Vinylquinoline (stabilised);2-Vinylquinoline 97%
• CAS NO: 772-03-2
• Molecular Formula: C₁₁H₉N
• Molecular Weight: 155.2
• EINECS: 212-246-8
• Product Categories: monomer;Fused Ring Systems
• Mol File: 772-03-2.mol
• Article Data: 23

Chemical Properties

• Melting Point: 284-285 °C
• Boiling Point: 269.01°C (rough estimate)
• Flash Point: 111.9 °C
• Appearance: dark orange-brown liquid
• Density: 1.0300
• Vapor Pressure: 0.0117mmHg at 25°C
• Refractive Index: 1.6210 (estimate)
• Storage Temp.: 2-8°C
• PKA: 4.88±0.40(Predicted)
• CAS DataBase Reference: 2-VINYLQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-VINYLQUINOLINE(772-03-2)
• EPA Substance Registry System: 2-VINYLQUINOLINE(772-03-2)

Safety Data

• Hazardous Substances Data: 772-03-2(Hazardous Substances Data)

Usage

Chemical Properties

dark orange-brown liquid

InChI:InChI=1/C11H9N/c1-2-10-8-7-9-5-3-4-6-11(9)12-10/h2-8H,1H2

Upstream product

• 1613-34-9 2-ethylquinoline 
• 1011-50-3 2-quinolin-2-yl-ethanol 
• 63487-23-0 β-N,N-dimethylaminoethylquinaldine 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 109586-44-9 trifluoromethanesulfonic acid quinolin-2-yl ester 
• 94829-51-3 2-oxiranyl-quinoline 
• 7647-01-0 hydrogenchloride 
• 64-19-7 acetic acid 
• 612-62-4 2-Chloroquinoline 
• 1826-67-1 vinyl magnesium bromide 
• 5470-96-2 quinoline 2-carbaldehyde 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 91-22-5 quinoline 
• 1613-37-2 Quinoline N-oxide 

Downstream Products

• 102022-17-3 1-phenyl-4-(quinolin-2-yl)butan-1-one 
• 113039-53-5 4-[2]quinolyl-2-methyl-1-phenyl-butan-1-one 
• 47304-84-7 Diethyl-2-(2-guinoyl)ethylmalonat 
• 57961-97-4 2-[2-(4-methyl-piperazin-1-yl)-ethyl]-quinoline 
• 57961-89-4 2-[2-(4-phenyl-piperazin-1-yl)-ethyl]-quinoline 
• 57961-90-7 Centhaquin 
• 57962-04-6 1-(β-phenethyl)-4-(β-2-quinolylethyl)piperazine 
• 57961-96-3 2-{2-[4-(4-chloro-phenyl)-piperazin-1-yl]-ethyl}-quinoline 
• 57961-98-5 2-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethyl}-quinoline 
• 57961-94-1 2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-quinoline 
• 57962-01-3 2-{2-[4-(3,4-dichloro-phenyl)-piperazin-1-yl]-ethyl}-quinoline 
• 53981-06-9 benzyl-methyl-(2-quinolin-2-yl-ethyl)-amine 
• 57962-03-5 2-{2-[4-(3,4-dimethyl-phenyl)-piperazin-1-yl]-ethyl}-quinoline 
• 57962-06-8 2-{2-[4-(3-fluoro-phenyl)-piperazin-1-yl]-ethyl}-quinoline 

Relevant articles and documents

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The photoredox-catalyzed hydrosulfamoylation of styrenes and its application in the novel synthesis of naratriptan

The hydrosulfamoylation of diverse aryl olefins provides facile access to alkylsulfonamides. Here we report a novel protocol utilizing radical-mediated addition and a thiol-assisted strategy to achieve the hydrosulfamoylation of diverse styrenes in modest to excellent yields under mild and economic reaction conditions. The methodology was found to provide an efficient and convenient approach for the synthesis of the anti-migraine drug naratriptan and it also can be used for the late-stage functionalization of natural products or medicines.

SULFONYL-SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS ROR INHIBITOR

Provided is a sulfonyl-substituted bicyclic compound (A) which acts as a RORγ inhibitor, said compound has good RORγ inhibitory activity and is expected to be used for treating diseases mediated by a RORγ receptor in mammals.

Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines

Cu-catalyzed three-component couplings of vinylazaarenes, B2(pin)2, and N-Boc imines are described. Oxidation of the initially formed boronate gives azaarene-containing, Boc-protected amino alcohols with reasonable to good diastereoselectivities.