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Chlorosulfuric acid, 4-methylphenyl ester, also known as 4-methylphenyl chlorosulfate, is an organic compound with the chemical formula C7H7ClO3S. It is a colorless to pale yellow liquid that is soluble in organic solvents. Chlorosulfuric acid, 4-methylphenyl ester is formed by the esterification of chlorosulfuric acid with 4-methylphenol (also known as p-cresol). It is primarily used as a chemical intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactivity, it is important to handle Chlorosulfuric acid, 4-methylphenyl ester with care, as it can be corrosive and may cause irritation to the skin, eyes, and respiratory system.

772-80-5

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772-80-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 772-80-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,7 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 772-80:
(5*7)+(4*7)+(3*2)+(2*8)+(1*0)=85
85 % 10 = 5
So 772-80-5 is a valid CAS Registry Number.

772-80-5Relevant academic research and scientific papers

Tetrahydrocoptisine derivative and applications thereof

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Paragraph 0422; 0423; 0424, (2016/10/08)

The present invention relates to a compound as shown in a formula (VII), a preparation method and applications thereof in medicines. In particular, the present invention relates to a derivative of the compound as shown in the formula (VII), a preparation method, and the applications of the derivative used as a therapeutic agent in prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, II-type diabetes, hyperglycemia, obesity or insulin resistance syndrome and metabolic syndrome. The compound disclosed by the present invention can also reduce total cholesterol, LDL-cholesterol and triglyceride, and increases expression of a liver LDL receptor and decreases expression of PCSK9.

Synthesis of aryl sulfonamides via palladium-catalyzed chlorosulfonylation of arylboronic acids

Debergh, J. Robb,Niljianskul, Nootaree,Buchwald, Stephen L.

supporting information, p. 10638 - 10641 (2013/08/23)

A palladium-catalyzed method for the preparation of sulfonamides is described. The process exhibits significant functional group tolerance and allows for the preparation of a number of arylsulfonyl chlorides and sulfonamides under mild conditions.

From homogeneous to heterogeneous catalysis of the three-component coupling of oxysulfonyl azides, alkynes, and amines

Yang, Tao,Cui, Hao,Zhang, Changhe,Zhang, Li,Su, Cheng-Yong

, p. 3131 - 3138 (2013/10/21)

A reliable procedure for the synthesis of oxysulfonyl azides has been developed and applied to the three-component coupling reactions of azides, alkynes, and amines catalyzed homogeneously by CuI, which led to the formation of N-oxysulfonyl amidines with

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