77220-86-1

Usage

Uses

Used in Sports Nutrition:
4-hydroxy-3-methyl-butanoic acid is used as a dietary supplement for athletes and individuals seeking to improve their physical performance. It helps in reducing muscle protein breakdown, promoting muscle protein synthesis, and improving muscle recovery after intense exercise, thereby enhancing athletic performance.
Used in Elderly Care:
4-hydroxy-3-methyl-butanoic acid is used as a supplement for elderly individuals to help preserve muscle mass and strength. It may have potential benefits in maintaining muscle health and preventing muscle loss associated with aging.

InChI:InChI=1/C5H10O3/c1-4(3-6)2-5(7)8/h4,6H,2-3H2,1H3,(H,7,8)

Upstream product

• 188692-77-5 (3S)-4-<(1-ethoxyethyl)oxy>-3-methylbutanenitrile 
• 44647-19-0 (E)-4-hydroxy-3-methylbut-2-enoic acid 
• 97-65-4 2-methylenesuccinic acid 
• 80573-34-8 α,β-dibromo-β,β-dimethylpropionic acid 
• 1578-14-9 2-bromo-3-methyl-crotonic acid 
• 71424-95-8 (-)-4-Amino-3-methyl-buttersaeure 

Downstream Products

• 88408-99-5 (2S)-4-(benzyloxy)-1-(phenylsulfonyl)-2-methylbutane 
• 156593-01-0 1-O-benzyl-2,3-bis-O-<(3R,7R,11S,15S)-16-<(tert-butyldimethylsilyl)oxy>-3,7,11,15-tetramethylhexadecanyl>-sn-glycerol 
• 156593-03-2 (2S,6S,10R,14R)-16-[(S)-2-Benzyloxy-1-((3R,7R,11S,15S)-3,7,11,15-tetramethyl-16-oxo-hexadecyloxymethyl)-ethoxy]-2,6,10,14-tetramethyl-hexadecanal 
• 156593-02-1 1-O-benzyl-2,3-bis-O-<(3R,7R,11S,15S)-16-hydroxy-3,7,11,15-tetramethylhexadecanyl>-sn-glycerol 
• 188692-83-3 (2S,6R,10S,14R)-16-(benzyloxy)-1-<(tert-butyldimethylsilyl)oxy>-2,6,10,14-tetramethyl-8-(phenylsulfonyl)hexadecane 
• 188692-79-7 (2S,6S)-8-(benzyloxy)-1-<(tert-butyldimethylsilyl)oxy>-2,6-dimethyl-5-(phenylsulfonyl)octane 
• 156592-97-1 (2S,6R)-8-(benzyloxy)-1-(phenylsulfonyl)-2,6-dimethyloctane 
• 156592-96-0 (2S,6S)-8-(benzyloxy)-1-<(tert-butyldimethylsilyl)oxy>-2,6-dimethyloctane 
• 66261-34-5 (2S,6R)-8-(benzyloxy)-2,6-dimethyloctanol 
• 66261-30-1 (S)-4-(benzyloxy)-2-methylbutan-1-ol 

Relevant academic research and scientific papers

Aqueous-phase hydrogenation of biomass-derived itaconic acid to methyl-γ-butyrolactone over Pd/C catalysts: Effect of pretreatments of active carbon

The effect of active carbon pretreatment on the catalytic performance of Pd/C catalysts in the hydrogenation of itaconic acid was studied. The catalysts were prepared by deposition-precipitation and characterized by XRD, BET, NH3-TPD, TEM and F

Highly regioselective intramolecular hydroxymethylation of α,β-unsaturated carboxylic acids

A convenient synthesis of hydroxy esters 7 and lactones 8 by starting from easily available α,β-unsaturated carbocylic acids 4 is described. The key step of this transformation is a hitherto unknown radical cyclization of silyl esters, which exhibits a high degree of regioselectivity through steric and orbital control.

The First Synthesis of an Archaebacterial 36-Membered Macrocyclic Diether Lipid

The archaebacterial macrocyclic diether lipid featuring of 36-membered ring is synthesized by the McMurry coupling as a key step.

Asymmetric Hydrogenation of Unsaturated Carboxylic Acids Catalyzed by BINAP-Ruthenium(II) Complexes

Homogeneous hydrogenation of α,β- or β,γ-unsaturated carboxylic acids in the presence of a catalytic amount of Ru(OCOCH3)2 affords the corresponding saturated products in high enantiomeric excesses and in quantitative yields.The new hydrogenation has been applied to the asymmetric synthesis of (S)-naproxen, a 1β-methylcarbapenem precursor, and some methylated γ- and δ-lactones