77257-42-2 Usage
Uses
Different sources of media describe the Uses of 77257-42-2 differently. You can refer to the following data:
1. Antispasmodic.
2. MG 624 is an antagonist of neuronal AChR.
Brand name
Elvetil (Maggioni Farmaceutici S.p.A., Italy).
Biological Activity
A selective antagonist for neuronal α 7 subunit- containing nAChR subtypes. Inhibits α -Bgtx binding to chick α 7 and α 4 β 2 subtypes with K i values of 106 nM and 84 μ M respectively.
Check Digit Verification of cas no
The CAS Registry Mumber 77257-42-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,2,5 and 7 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 77257-42:
(7*7)+(6*7)+(5*2)+(4*5)+(3*7)+(2*4)+(1*2)=152
152 % 10 = 2
So 77257-42-2 is a valid CAS Registry Number.
InChI:InChI=1/C22H30NO.HI/c1-4-23(5-2,6-3)18-19-24-22-16-14-21(15-17-22)13-12-20-10-8-7-9-11-20;/h7-17H,4-6,18-19H2,1-3H3;1H/q+1;/p-1/b13-12+;
77257-42-2Relevant articles and documents
Synthesis of trans-N,N,N-triethyl-2-ethanammonium iodide
Al-Hassan, Mohammed I.
, p. 395 - 397 (2007/10/02)
The antispasmodic olefin trans-N,N,N-triethyl-2-ethanammonium iodide has been made by hydroalumination of a trimethylsilylalkyne followed by palladium-catalyzed cross-coupling of the vinylalane with the appropriate aryl bromide.
