77276-61-0Relevant articles and documents
2-Oxo-1,8-naphthyridine-3-carboxylic Acid Derivatives with Potent Gastric Antisecretory Properties
Santilli, Arthur A.,Scotese, Anthony C.,Bauer, Raymond F.,Bell, Stanley C.
, p. 2270 - 2277 (1987)
The syntheses of 2-oxo-1,8-naphthyridine-3-carboxylic acid derivatives having potent gastric antisecretory properties in the pyloric-ligated (Shay) rat model are described.Two of the more potent compounds tested that were selected for more detailed dose-r