
Journal of Medicinal Chemistry p. 2270 - 2277 (1987)
Update date:2022-09-26
Topics:
Santilli, Arthur A.
Scotese, Anthony C.
Bauer, Raymond F.
Bell, Stanley C.
The syntheses of 2-oxo-1,8-naphthyridine-3-carboxylic acid derivatives having potent gastric antisecretory properties in the pyloric-ligated (Shay) rat model are described.Two of the more potent compounds tested that were selected for more detailed dose-r
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