77290-62-1Relevant academic research and scientific papers
A chiral cobalt(II) complex catalyzed asymmetric formal [3+2] cycloaddition for the synthesis of 1,2,4-triazolines
Ma, Baiwei,Luo, Weiwei,Lin, Lili,Liu, Xiaohua,Feng, Xiaoming
supporting information, p. 4077 - 4079 (2017/04/13)
A highly efficient catalytic asymmetric formal [3+2] cycloaddition reaction of 5-alkoxyoxazoles with azodicarboxylate compounds has been realized by a chiral N,N′-dioxide/Co(BF4)2·6H2O complex. A series of poly-substituted 1,2,4-triazolines compounds were obtained in moderate to excellent yields (70-99%) with excellent enantioselectivities (82-98% ee).
Metalloporphyrin-promoted rearrangement of 2-alkyloxaziridines
Suda,Umehara,Hino
, p. 839 - 841 (2007/10/02)
Transformation of 2-alkyloxaziridines to the corresponding amides is efficiently catalyzed by high-valent metalloporphyrins. This novel rearrangement was used to create a peptide bond and the precursor of a dipeptide ''aspartame'' was obtained in good yield.
