77291-92-0

Basic information

• Product Name: 1,3-Propanediol, 1,3-diphenyl-, (1R,3R)-
• Synonyms: (+)-(R,R)-1,3-diphenyl-1,3-propanediol;anti-(R,R)-1,3-diphenyl-1,3-propanediol;(1R,3R)-1,3-Diphenyl-1,3-propanediol;(R,R)-(+)-1,3-diphenylpropane-1,3-diol;(1R,3R)-1,3-Diphenyl-propane-1,3-diol;(R,R)-1,3-diphenylpropane-1,3-diol;(1R,3R)-1,3-diphenylpropane-1,3-diol
• CAS NO: 77291-92-0
• Molecular Formula: C15H16O2
• Molecular Weight: 228.291
• Mol File: 77291-92-0.mol
• Article Data: 54

Chemical Properties

• CAS DataBase Reference: 1,3-Propanediol, 1,3-diphenyl-, (1R,3R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Propanediol, 1,3-diphenyl-, (1R,3R)-(77291-92-0)
• EPA Substance Registry System: 1,3-Propanediol, 1,3-diphenyl-, (1R,3R)-(77291-92-0)

Safety Data

• Hazardous Substances Data: 77291-92-0(Hazardous Substances Data)

Upstream product

• 42052-51-7 3-hydroxy-1,3-diphenylpropan-1-one 
• 100-52-7 benzaldehyde 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 120-46-7 1,3-diphenylpropanedione 
• 5381-86-2 (+/-)-(RS,RS)-1,3-diphenyl-1,3-propanediol 
• 123-62-6 propionic acid anhydride 
• 100-42-5 styrene 
• 7570-85-6 trans-2,3-epoxy-1,3-diphenyl-1-propanone 
• 57786-91-1 1,3-diphenylpropane-1,3-diol diacetate 
• 60-29-7 diethyl ether 
• 62961-62-0 (Z)-3-hydroxy-1,3-diphenyl-2-propen-1-one 
• 1674-30-2 1-phenyl-2-chloroethanol 
• 67931-44-6 1-bromomercurio-2-hydroxy-2-phenylethane 
• 103-30-0 (E)-1,2-diphenyl-ethene 

Downstream Products

• 5381-90-8 racem.-1,3-bis-benzoyloxy-1,3-diphenyl-propane 
• 26278-69-3 1,3-diphenyl-1,3-dimethoxy propane 
• 7107-24-6 1,3-diphenyl-1-methoxy-3-hydroxy propane 
• 120-46-7 1,3-diphenylpropanedione 
• 108391-15-7 (1S,3S)-1,3-diphenylpropane-1,3-diol 
• 57786-91-1 1,3-diphenylpropane-1,3-diol diacetate 
• 250281-46-0 (+)-(R,R)-1,3-dicyclohexyl-1,3-propanediol 
• 1454311-18-2 1,3-bis[(diphenylphosphino)oxy]-1,3-diphenylpropane 

Relevant articles and documents

Horeau amplification in the sequential acylative kinetic resolution of (±)-1,2-diols and (±)-1,3-diols in flow

The sequential acylative kinetic resolution (KR) of C2-symmetric (±)-1,2-syn and (±)-1,3-anti-diols using a packed bed microreactor loaded with the polystyrene-supported isothiourea, HyperBTM, is demonstrated in flow. The sequential KRs of C2-symmetric (±)-1,2-syn and (±)-1,3-anti-diols exploits Horeau amplification, with each composed of two successive KR processes, with each substrate class significantly differing in the relative rate constants for each KR process. Optimisation of the continuous flow set-up for both C2-symmetric (±)-1,2-syn and (±)-1,3-anti-diol substrate classes allowed isolation of reaction products in both high enantiopurity and yield. In addition to the successful KR of C2-symmetric (±)-1,2-syn and (±)-1,3-anti-diols, the application of this process to the more conceptually-complex scenario involving the sequential KR of C1-symmetric (±)-1,3-anti-diols was demonstrated, which involves eight independent rate constants. This journal is

NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS

The present invention relates to novel phosphorous (V) (P(V)) reagents, methods for preparing thereof, and methods for preparing organophosphorous (V) compounds by using the novel reagents.

Double Catalytic Kinetic Resolution (DoCKR) of Acyclic anti-1,3-Diols: The Additive Horeau Amplification

The concept of a synergistic double catalytic kinetic resolution (DoCKR) as described in this article was successfully applied to racemic acyclic anti-1,3-diols, a common motif in natural products. This process takes advantage of an additive Horeau amplif