7730-87-2

Usage

Uses

Used in Pharmaceutical Industry:
1-METHYLPIPERIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE is used as an intermediate compound for the synthesis of various pharmaceutical products. Its unique chemical structure allows it to be a key component in the development of new drugs, particularly those targeting the central nervous system.
Used in Chemical Synthesis:
In the field of chemical synthesis, 1-METHYLPIPERIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE serves as a valuable building block for creating a wide range of chemical compounds. Its versatility in reacting with other molecules makes it a useful tool for researchers and chemists in developing new materials and products.
Used in Agricultural Industry:
1-METHYLPIPERIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE can be utilized in the agricultural industry as a component in the development of new pesticides or herbicides. Its chemical properties may contribute to the effectiveness of these products in controlling pests and weeds, ultimately leading to increased crop yields and improved food security.
Used in Research and Development:
Due to its unique chemical properties, 1-METHYLPIPERIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE is an important compound in research and development. It can be used in various experimental setups to study its interactions with other molecules and to explore its potential applications in different fields, such as materials science, pharmaceuticals, and biotechnology.

Upstream product

• 626-67-5 N-methylcyclohexylamine 
• 124-38-9 carbon dioxide 
• 30727-18-5 ethyl 1-methylpiperidine-2-carboxylate 

Downstream Products

• 20845-34-5 (1-methyl-piperidin-2-yl)-methanol 
• 945423-49-4 1-methyl-piperidine-2-carboxylic acid (2'-methyl-5'-oxazol-2-yl-biphenyl-4-yl)-amide 
• 58754-48-6 encainide 
• 921928-01-0 (R)-perfluorophenyl 1-methylpiperidine-2-carboxylate 
• 1123512-46-8 N-(5-(5-(4-(difluoromethoxy)phenyl)pyrimidin-2-ylamino)-2-methylphenyl)-1-methylpiperidine-2-carboxamide 
• 108239-53-8 1-methyl-piperidine-2-carboxylic acid benzylamide 
• 113061-48-6 1-methyl-piperidine-2-carboxylic acid-(4-butoxy-2,6-dimethyl-anilide) 
• 110154-90-0 1-methyl-piperidine-2-carboxylic acid-(4-butoxy-2-methyl-anilide) 
• 101353-77-9 1-methyl-piperidine-2-carboxylic acid-(N-ethyl-anilide) 

Relevant academic research and scientific papers

Photolysis of Tertiary Amines in the Presence of CO2: The Paths to Formic Acid, α-Amino Acids, and 1,2-Diamines

The photolysis of triethylamine (1a) in the presence of carbon dioxide leads to the hydrogenation of CO2, the α-C-C coupling of 1a, and the CO2 insertion into the α-C-H σ-bond of amine 1a. This reaction is proposed to proceed through the radical ion pair [R3N?+·CO2?-] generated by the photoionization of amine 1a and the electron capture by CO2. The presence of lithium tetrafluoroborate in the reaction medium promotes the efficient and stereoselective α-C-C coupling of 1a by enhancing the production of α-dialkylamino radicals and the isomerization of N,N,N′,N′-tetraethylbutane-2,3-diamine (4a).

Mechanism of elimination of amino acid derivatives in the gas phase. Pyrolysis kinetics of ethyl picolinate, ethyl 1-methylpipecolinate and picolinic acid

The kinetics of the gas-phase elimination of the title compounds were determined in a static reaction system over the temperature range 180.8-419.4 °C and the pressure range 15-86 Torr (1 Torr = 133.3 Pa). The reactions are homogeneous and unimolecular and obey a first-order rate law. The observed rate coefficients are represented by the following Arrhenius equations: for ethyl picolinate, log[k1(s-1)] = (11.30 ± 0.24) -(180.9 ± 3.0) Kj mol-1 (2.303 RT)-1, for ethyl 1-methylpipecolinate, log[k1(s-1)] = (13.36 ± 0.31) -(209.5 ± 3.9) Kj mol-1 (2.303 RT)-1 and for picolinic acid, log[k1(s-1)] = (12.05 ± 0.10) -(135.7 ± 0.9) Kj mol-1 (2.303 RT)-1. The data from this work together with those reported in the literature confirm previous considerations that amino acids or α-nitrogen substituents of carboxylic acids undergo an extremely rapid decarboxylation process. The pyrolysis kinetics of picolinic acid, which is an intermediate of ethyl picolinate elimination, showed a dramatic fast decomposition into pyridine and CO2 gas. The decarboxylation process of α-amino or α-nitrogen substituents of carboxylic acids differs from the decarboxylation elimination of several known α-substituted carboxylic acids in the gas phase. Copyright