77301-47-4

Usage

Uses

Used in Pharmaceutical Industry:
3-Benzoyl Benzoyl Chloride serves as a crucial reagent in organic synthesis, particularly for the introduction of benzoyl groups into various molecular structures. Its application in this industry is instrumental in the development and manufacturing of pharmaceuticals, contributing to the creation of new drugs and medicinal compounds.
Used in Dye Industry:
In the dye industry, 3-Benzoyl Benzoyl Chloride is utilized for the synthesis of various dyes. Its ability to introduce benzoyl groups into molecules makes it a valuable component in the production of a range of colorants used in different applications, including textiles, plastics, and printing inks.
Used in Organic Compounds Synthesis:
Beyond its applications in pharmaceuticals and dyes, 3-Benzoyl Benzoyl Chloride is also employed in the synthesis of other organic compounds. Its reactivity and capacity to modify molecular structures make it a versatile agent in organic chemistry, facilitating the production of a diverse array of specialty chemicals and intermediates.

Upstream product

• 628-71-7 1-Heptyne 
• 98-88-4 benzoyl chloride 
• 77-75-8 meparfynol 
• 79-37-8 oxalyl dichloride 
• 579-18-0 3-benzoylbenzoic acid 
• 643-65-2 3-methyl benzophenone 

Downstream Products

• 96825-65-9 (3-benzoylphenyl)(3-methylphenyl)methanone 
• 96825-44-4 (3-benzoylphenyl)(2,4,6-triethylphenyl)methanone 
• 74997-34-5 3-benzoylbenzoic acid cholesteryl ester 
• 143471-18-5 (3,5,5-trimethyl-1-pyrazolin-3-yl)methyl 3-benzoylbenzoate 
• 183376-20-7 3-Benzoyl-benzoic acid (2E,6E)-8-(2-chloro-acetoxy)-2,6-dimethyl-octa-2,6-dienyl ester 
• 840523-84-4 2-acetylphenyl 3-benzoylbenzoate 
• 938163-33-8 C₁₆H₁₁NO₂ 
• 313350-98-0 N₁-[4-(4-Amino-1H-imidazo[4,5-c]quinolin-1-yl)butyl]-3-benzoylbenzamide 
• 135611-46-0 m-benzoyl-N-[3-(pyridin-3-yl)-1H,3H-pyrrolo[1,2-c]thiazol-7-yl]benzamide 
• 1107692-63-6 thien-2-ylmethyl 3-benzoylbenzoate 
• 1068580-79-9 C₃₁H₂₄O₈ 
• 328543-25-5 1-(3-Benzoylphenyl)-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one 
• 422550-77-4 3-benzoyl-N-methoxy-N-methylbenzamide 
• 96825-66-0 3-(3-benzoylbenzoyl)benzoyl chloride 

Relevant academic research and scientific papers

Addition-Isomerization Polymerization of Chiral Phosphaalkenes: Observation of Styrene-Phosphaalkene Linkages in a Random Copolymer

These studies provide the first evidence for styrene-phosphaalkene connectivities in a phosphaalkene copolymer. The synthesis and structural characterization of new phosphaalkene-oxazolines, ArPC(Ph)(3-C6H4Ox) [1a,b, Ar = Mes (1a), M

Palladium(II) on 4 ? Molecular Sieves: A Simple and Reusable Catalyst for the Preparation of Ynones

Abstract: Pd2+ on 4?? molecular sieves support has been prepared and investigated. The catalyst has successfully been used in the reaction of acyl chlorides and terminal alkynes yielding ynones. The catalyst can be reused without significant lo

De novo parallel design, synthesis and evaluation of inhibitors against the reverse transcriptase of human immunodeficiency virus type-1 and drug-resistant variants

We used molecular modeling to design de novo broad-range inhibitors against wild type and drug-resistant variants of the reverse transcriptase (RT) of human immunodeficiency virus type-1 (HIV-1). First, we screened for small fragments that would interact with each one of four RT structures (one wild type and three mutants). Then, these fragments were linked to build a scaffold molecule. Out of 27 different compounds that were synthesized, four inhibited the DNA polymerase activity of RT with IC50 values below 10 μM. Compound 5f inhibited RT with an IC50 value of about 3.5 μM, while inhibiting drug-resistant RT variants more efficiently than the clinically used drug, nevirapine (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b: 2′,3′-e-]-[1,4]diazepin-6-one). 5f also inhibited the RT ribonuclease H activity with an IC50 of 20 μM and therefore, unlike nevirapine, targets both RT activities. Accordingly, 5f can serve as lead for developing novel inhibitors against RT that may be used to suppress HIV-1 growth.

Aza-and polyaza-naphthalenly ketones useful as hiv integrase inhibitors

Certain aza- and polyaza-naphthalenyl ketones including certain quinolinyl and naphthyridinyl ketones are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment or the delay in the onset of AIDS, as compounds or pharmaceutically acceptable salts, or as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating or delaying the onset of AIDS and methods of preventing or treating infection by HIV are also described.

Synthesis of new potential HIV-1 integrase inhibitors

A synthesis of some 1,2-(hetero)arylsubstituted ethanone and 1,3-(hetero)arylsubstituted3-hydroxypropenone derivatives, designed as potential HIV-1 integrase inhibitors, is reported. The microwave-assisted synthesis was applied in several reactions achiev

Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists

The present invention provides compounds and pharmaceutical compositions that act as antagonists at metabotropic glutamate receptors, and that are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.

Self-sensitized photolysis of N-(1-naphthoyl)-N-phenyl-O-(benzoyl-substituted benzoyl)hydroxylamines

The mechanism of intramolecular triplet-triplet (T-T) energy transfer and subsequent reaction in N,O-diacylhydroxylamines was investigated using the model compounds N-( 1 -naphthoyl)-N-phenyl-O-(benzoyl-substituted benzoyl)hydroxylamines (NPB) with self-sensitization abilities. An examination of the UV absorption and phosphorescence behavior as well as of energy-minimized conformations of these relatively flexible model compounds established that T-T energy transfer from the benzophenone chromophore to the naphthoyl chromophore occurs in a nearly unit efficiency exhibiting only phosphorescence derived from the latter chromophore in both methanol-ethanol (1 : 1 v/v) and 2-chlorobutane at 77 K and is more likely to proceed by a "through-space" mechanism than by a "through-bond" mechanism. The self-sensitized photolysis of NPB with 366 nm light in methanol at room temperature was found to give the fragmentation products, N-phenyl-1-naphthalenecarboxamide (PNA), benzophenone (BP), and benzoyl-substituted benzoic acids (BBA), whereas no BBA was detected in the photolysis in 1,2-dichloroethane and acetonitrile. The finding that the reaction of NPB is efficiently quenched by trans-stilbene according to the Stern-Volmer equation in both methanol and 1,2-dichloroethane indicates that all the products come from the first excited triplet state of the naphthoyl chromophore. On the other hand, the enhanced hydrogen bonding ability of the medium resulted in an increase in the quantum yield for the formation of BBA (ΦBBA) accompanied by a decrease in ΦBA holding the magnitude of ΦBBA+ΦBA nearly constant. But neither ΦPNA nor the quantum yield for the disappearance of NPB was subject to such a hydrogen-bonding effect. This intriguing result was explained in terms of a mechanism in which the N-O bond cleavage in triplet NPB gives a vibrationally excited triplet radical pair whose relaxation is very slow compared to decarboxylation of the caged benzoyl-substituted benzoyloxyl radical in 1,2-dichloroethane. Solvation of this vibrationally hot radical pair through hydrogen bonding substantially promotes its relaxation eventually affording BBA.

Intramolecular Triplet Energy Transfer in Ester-Linked Bichromophoric Azoalkanes and Naphthalenes

The photophysics of a series of compounds has been studied wherein a triplet sensitizer such as benzophenone (BB) or thioxanthone (TH) is linked via an ester group to an azoalkane such as 3,3,5,5-tetramethyl-1-pyrazoline (PY) or 2,3-diazabicyclooct

Photochemistry of Meta-Substituted and Para-Substituted Aromatic Polycarbonyl Compounds

Spectroscopic (λmax and ET) and photochemical (quantum yield of benzocyclobutenol formation ΦCB and Stern-Volmer quenching constant with diene KSV) properties for meta-substituted polyketones 1b-f, 2, and 5b, pa

INFLUENCE OF THE ANGULAR LINKAGE ON THE MESOMORPHIC PROPERTIES OF CHOLESTERYL ARYLBENZOATES.

Some cholesteryl esters of arylbenzoic acids incorporating angular linkage such as -Co-, -O-, -S-, and -CH//2-, were prepared, and the transition temperatures and heats determined. The cholesteric-isotropic transition temperatures are likely to correlate with the angular correlation parameters of these carboxylic acid moieties. The mesomorphic phenomena are discussed in terms of the molecular structure and electronic effect of these linkages.