77317-57-8Relevant academic research and scientific papers
4-Hydroxy-2-quinolones. 112. Reaction of 2-ethoxycarbonylmethyl-4H-3,1- benzoxazin-4-one with active methylene compounds
Ukrainets,Sidorenko,Gorokhova,Slobodzyan
, p. 63 - 66 (2007)
The reaction of 2-ethoxycarbonylmethyl-4H-3,1-benzoxazin-4-one with malononitrile in dry pyridine leads to 1-hydroxy-3,6-dioxo-4,6-dihydro-3H- pyrimido[1,2-a]quinoline-5-carbonitrile. Acetoacetic and cyanoacetic esters under analogous conditions form anil
Ethyl Esters of Malonanilic Acids. Synthesis and Pyrolysis
Ukrainets, Igor V.,Bezugly, Peter A.,Treskach, Vladimir I.,Taran, Svetlana G.,Gorokhova, Olga V.
, p. 10331 - 10338 (2007/10/02)
The pyrolysis under 170-220 deg C or boiling in DMF of malonanilic acids ethyl esters (2) is accompanied by formation of malonic acids symmetric dianilides (7) with high yields.A possible mechanism for this transformation has been suggested.
2-CARBETHOXY-4H-3,1-BENZOXAZIN-4-ONE. 1. SYNTHESIS AND REACTION MECHANISM OF FORMATION
Ukrainets, I. V.,Bezuglyi, P. A.,Treskach, V. I.,Slobodzyan, S. V.
, p. 903 - 907 (2007/10/02)
The possibility was examined of using various condensing agents in the intramolecular cyclization reaction of ethyl ester of 2-carbomalonanilic acid into 2-carboethoxymethyl-4H-3,1-benzoxazin-4-one.It was found that the optimal reagent is dicyclohexylcarbodiimide.By using NMR spectroscopy and deutero-exchange it was shown that the cyclization proceeds with the participation of the hydroxyl group of the carboxyl and a proton of the amide function.
ACYLATION OF ORTHO(PARA)-SUBSTITUTED AROMATIC AMINES BY MALONIC ACID DERIVATIVES
Bezuglyi, P. A.,Treskach, V. I.,Ukrainets, I. V.,Grinenko, V. V.,Bevz, N. Yu.
, p. 1233 - 1236 (2007/10/02)
The reaction of diethyl malonate with primary ortho(para)-substituted arylamines leads to the formation of ethyl malonanilates or symmetrical malonanilides, depending on the temperature and on the nucleophilic characteristics of the amines.
[(1,3-dioxo-1,3-propanediyl)diimino)]bisbenzoic acid derivatives
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, (2008/06/13)
Compounds of the general formula: STR1 wherein A and B are both hydrogen, or one of A and B is a group (G) of the formula: STR2 and the other is a group R5 wherein R1 is an aryl group or a heterocyclic group, both of them being optio
