77342-84-8

Upstream product

• 77358-87-3 5-Methoxy-1-phenyl-1,4-pentandion 
• 105872-18-2 3-chloro-2-hydroxycyclopent-2-enone 
• 28742-35-0 3-bromo-2-methoxy-2-cyclopenten-1-one 
• 98-80-6 phenylboronic acid 
• 3008-40-0 cyclopentane-1,2-dione 
• 98198-83-5 3-chloro-2-methoxycyclopent-2-en-1-one 

Relevant academic research and scientific papers

Synthesis of Cyclic 3-Aryl-Substituted 1,2-Dicarbonyl Compounds via Suzuki Cross-Coupling Reactions

A method for the synthesis of cyclic 3-aryl and heteroaryl-substituted 1,2-dicarbonyl compounds with different ring sizes by using a Suzuki cross-coupling reaction between 3-halo-1,2-dicarbonyl compounds and arylboronic acids is developed. The 3-halo-1,2-dicarbonyl substrates are easily available from 1,2-dicarbonyl compounds. The method is versatile, affording good to high yields of the target compounds.

Addition of Aldehydes to Activated Double Bonds, XXVIII. Preparations and Reactions of Alkoxy- and Acetoxy-2,5-diones

Thiazolium salt-catalyzed addition of aliphatic ether-aldehydes and pyrancarbaldehydes leads to corresponding 1-alkoxy-2,5-alkanediones 1-11 and pyranyl-1,4-alkanediones 28 - 47.In the same manner aldehydes react with 1-acetoxy-3-buten-2-one to give 1-acetoxy-2,5-alkanediones 12 - 19, which after saponification yield the 1-hydroxy-5-alkyl-2,5-pentanediones 20 - 27.