77356-41-3

Upstream product

• 100-39-0 benzyl bromide 
• 70209-54-0 Benzyl-2-acetamido-3,6-di-O-benzyl-2-desoxy-4-O-(β-D-galactopyranosyl)-α-D-glucopyranosid 
• 55287-49-5 benzyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 14146-27-1 benzyl 3-O-benzyl-2-acetamido-2-deoxy-α-D-glucopyranoside 
• 58700-48-4 Benzyl-2-acetamido-3,6-di-O-benzyl-2-desoxy-4-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-α-D-glucopyranosid 
• 77396-73-7 benzyl 2-acetamido-4-O-(2,6-di-O-benzyl-3,4-O-isopropylidene-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 

Downstream Products

• 77356-42-4 benzyl 2-acetamido-4-O-(3,4-di-O-acetyl-2,6-di-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 77356-47-9 benzyl 2-acetamido-4-O-(2,3,6-tri-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 77356-44-6 benzyl 2-acetamido-4-O-<2,6-di-O-benzyl-3-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-β-D-galactopyranosyl>-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 78635-88-8 C₇₅H₉₀N₂O₂₇ 
• 77356-43-5 Acetic acid (2R,3S,4S,5R,6S)-6-((2R,3S,4R,5R,6S)-5-acetylamino-4,6-bis-benzyloxy-2-benzyloxymethyl-tetrahydro-pyran-3-yloxy)-4,5-bis-benzyloxy-2-benzyloxymethyl-tetrahydro-pyran-3-yl ester 
• 59446-75-2 Galα(1->3)Galβ(1->4)GlcNAc 

Relevant academic research and scientific papers

Blood-group Ii-Active Oligosaccharides. Synthesis of a Tetrasaccharide, a β-(1->3) Dimer of N-Acetyl-lactosamine

Condensation of benzyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside (2) with 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl bromide, followed by de-O-acetylation, acetonation, O-benzoylation, and acidic hydrolysis afforded the 3',4'-diol (5) derived from N-acetyl-lactosamine.This compound was selectively glycosylated at the 3'-position by the oxazoline (7) derived from lactosamine to give the protected tetrasaccharide (8) in 52percent yield.Removal of the protecting groups gave the free tetrasaccharide β-D-Galp-(1->4)-β-D-GlcpNAc-(1->3)-β-D-Galp-(1->4)-D-GlcpNAc (9), a β-(1->3) dimer of N-acetyl-lactosamine.This structure has been found in various glycolipids isolated from erythrocyte membranes and could be recognized by several anti-i antisera.

Synthesis of Blood-group Substances. Part 11. Synthesis of the Trisaccharide O-α-D-Galactopyranosyl-(1-->3)-O-β-D-galactopyranosyl-(1-->4)-2-acetamido-2-deoxy-D-glucopyranose

Reaction of 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl bromide with benzyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside in 1,2-dichloroethane in the presence of mercuric bromide and molecular sieves (4 Angstroem) provided after O-deacetylation