773826-73-6

Basic information

• Product Name: tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate
• Synonyms: tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate;3-(Aminomethyl)-4-hydroxy-1-pyrrolidinecarboxylic acid tert-butyl ester;tert-Butyl 3-(aminomethyl)-4-hydroxy-1-pyrrolidinecarboxylate
• CAS NO: 773826-73-6
• Molecular Formula: C₁₀H₂₀N₂O₃
• Molecular Weight: 216.2774
• Mol File: 773826-73-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.146
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate(773826-73-6)
• EPA Substance Registry System: tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate(773826-73-6)

Safety Data

• Hazardous Substances Data: 773826-73-6(Hazardous Substances Data)

Usage

General Description

"Tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate" is a chemical compound with the molecular formula C11H22N2O3. It is a derivative of pyrrolidine, a cyclic amine, and contains a tert-butyl group and a carboxylate group. tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, due to its potential biological activity. It may also be used as a building block for the creation of new compounds with specific properties. Due to its structural features and potential applications, this chemical is of interest to researchers and industry professionals in the fields of medicinal chemistry, organic synthesis, and chemical biology.

Upstream product

• 266353-18-8 N-tert-butoxycarbonyl-2-(2-cyanoethyl)aminoacetic acid ethyl ester 
• 175463-32-8 3-cyano-4-oxopyrrolidine-1-carboxylic acid tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 44981-94-4 N-cyanoethyl glycine ethyl ester 
• 197143-33-2 tert-butyl 3-cyano-4-hydroxypyrrolidine-1-carboxylate 

Downstream Products

• 175463-34-0 4-(tert-butoxycarbonyl)aminomethyl-1-(t-butoxycarbonyl)pyrrolidin-3-ol 
• 872716-50-2 1,1-dimethylethyl 3-hydroxy-4-[({[(phenylmethyl)oxy]carbonyl}amino)methyl]-1-pyrrolidinecarboxylate 
• 175463-14-6 gemifloxacin 

Relevant articles and documents

Preparation and application of imidazo aromatic ring compounds

The invention provides preparation and application of imidazo aromatic ring compounds, and particularly provides compounds as shown in the following formula I. The definition of each group is as shownin the specification. The compounds have TRK kinase inh

Discovery of gemifloxacin (Factive, LB20304a): A quinolone of new a generation

Novel quinolone antibacterials, which bear an alkyloxime substituent in the 4-position and an aminomethyl substituent in the 3-position of the pyrrolidine ring, have been designed and synthesized. These fluoroquinolones were found to possess extremely potent antimicrobial activity against Gram-positive organisms including resistant strains such as methicillin-resistant Staphylococcus aureus (MRSA). Among these compounds our development candidate, Gemifloxacin (Factive, LB20304a), showed the best in vivo efficacy and pharmacokinetic profile in animals, as well as good safety pharmacological properties. Gemifloxacin was found to be especially effective against respiratory tract infections that account for over 70% of all infections. With once-a-day dosage, potency against respiratory tract infections such as chronic bronchitis and pneumonia was ensured without any significant side effect. In December 1999, Gemifloxacin filed a NDA for marketing approval to the US Food and Drug Administration. Copyright