77396-81-7

Upstream product

• 4124-41-8 p-toluenesulfonylanhydride 
• 74288-40-7 (5R,6S)-6-(1-Hydroxy-ethyl)-3,7-dioxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 4-nitro-benzyl ester 

Downstream Products

• 64067-13-6 (5R,6S)-6-(1-Hydroxy-ethyl)-3-[2-(4-nitro-benzyloxycarbonylamino)-ethylsulfanyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 77396-87-3 bis-[2-(phenoxyacetyl-amino)-ethyl]-disulfide 
• 77396-86-2 {(3S,4R)-3-(1-Hydroxy-ethyl)-2-oxo-4-[2-(2-phenoxy-acetylamino)-ethylsulfanylcarbonylmethyl]-azetidin-1-yl}-acetic acid 4-nitro-benzyl ester 
• 77396-85-1 3-Hydroxy-5-{2-hydroxy-1-[2-(2-phenoxy-acetylamino)-ethylsulfanylcarbonyl]-propyl}-1H-pyrrole-2-carboxylic acid 4-nitro-benzyl ester 

Relevant academic research and scientific papers

A facile transformation of bicyclic keto esters to bisprotected (±)-8-epithienamycin via enol activation

A facile "one-pot" transformation of bicyclic keto ester (2) to bisprotected (±)-8-epithienamycin via enol phosphate activation followed by the addition-elimination reaction of N-protected cysteamine derivative is described.