A facile transformation of bicyclic keto esters to bisprotected (±)-8-epithienamycin via enol activation

DOI: 10.1016/S0040-4039(00)92867-3

Source and publish data:

Tetrahedron Letters p. 4221 - 4224 (1980)

Update date:2022-07-31

Topics:

Authors:

Sletzinger

Liu Liu

Reamer Reamer

Shinkai Shinkai

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)92867-3

A facile "one-pot" transformation of bicyclic keto ester (2) to bisprotected (±)-8-epithienamycin via enol phosphate activation followed by the addition-elimination reaction of N-protected cysteamine derivative is described.

Full text of DOI:10.1016/S0040-4039(00)92867-3

Products guided by the article

Product name:(5R,6S)-6-(1-Hydroxy-ethyl)-7-oxo-3-(toluene-4-sulfonyloxy)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester

Cas No:77396-81-7

R&D Labs maybe for 77396-81-7

Ceresking Ecology & Technology co.,ltd

Contact:86 22 66218397

Address:Room 1613, Zheshang Mansion, No. 1988, Yingbin Avenue, Binhai New District, Tianjin,China.
Mashilabs(shanghai)Co.,ltd

Contact:+86-21-54391580

Address:Room 502,No.65,Lane 2388 Hongxin Road,Shanghai,China
Shijiazhuang Yunxuan Im&Export Co.,Ltd.

Contact:+86-311-83037514

Address:No.6 Hongbin Road
Lyrin Industrial Corporation Limited

Contact:86-731-82571800

Address:Rm 2408,Asia Economy International Building,Shaoshan Road South,Yuhua District,Changsha,Hunan,China
Chengdu Push Bio-technology Co., Ltd

Contact:--

Address:No.8 Wuke West Second Road, Wuhou

Relevant to this article

vic-Iodothiocyanates and Iodoisothiocyanates. Part 3. Further Preperations, and the Formation of 2-Alkoxy-2-thiazolines

Doi:10.1039/P19810000033
(1981)
NEW ROUTES TO 5,8,8-TRIPHENYLBENZOHEPTAFULVENES FROM (3,4-BIS(DIPHENYLMETHYLENE)-2-OXOCYCLOBUTYLIDENE)TRIPHENYLPHOSPHORANE. ISOLATION OF EXCESSIVELY STABILIZED BETAINE.

Doi:10.1016/0040-4039(80)80162-6
(1980)
Chirality Transfer via Organopalladium Chemistry. A Synthesis of Optically Active Vitamin E Side Chain from D-Glucose

Doi:10.1021/ja00397a059
(1981)
Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis

Doi:10.1021/acs.jmedchem.6b01718
(2017)
Selective [3 + 2] Cycloaddition of Cyclopropenone Derivatives and Elemental Chalcogens

Doi:10.1021/acs.orglett.0c01914
(2020)
Synthesis of 2-Arylpyridopyrimidinones, 6-Aryluracils, and Tri- and Tetrasubstituted Conjugated Alkenes via Pd-Catalyzed Enolic C-O Bond Activation-Arylation

Doi:10.1021/acs.joc.5b00771
(2015)

Article Doi