A facile transformation of bicyclic keto esters to bisprotected (±)-8-epithienamycin via enol activation

DOI: 10.1016/S0040-4039(00)92867-3

Source and publish data:

Tetrahedron Letters p. 4221 - 4224 (1980)

Update date:2022-07-31

Topics:

Authors:

Sletzinger

Liu Liu

Reamer Reamer

Shinkai Shinkai

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Article abstract of DOI:10.1016/S0040-4039(00)92867-3

A facile "one-pot" transformation of bicyclic keto ester (2) to bisprotected (±)-8-epithienamycin via enol phosphate activation followed by the addition-elimination reaction of N-protected cysteamine derivative is described.

Full text of DOI:10.1016/S0040-4039(00)92867-3

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