7740-65-0Relevant academic research and scientific papers
Nickel Catalyzed Reaction of Iodofluoroacetates with Alkenes as a Facile Route to α-Fluoroesters
Wang, Yong,Yang, Zhen-Yu,Burton, Donald J.
, p. 2137 - 2140 (2007/10/02)
Reaction of iodofluoroacetates with alkenes and zinc in the presence of nickel dichloride hexahydrate and pyridine in THF affords the corresponding α-fluoroesters in good yields.
Studies on Organic Fluorine Compounds. Part 37. Studies on Steroids. Part 78. Synthesis of 24,24-Difluoro- and 24ξ-Fluoro-25-hydroxyvitamin D3
Kobayashi, Yoshiro,Taguchi, Takeo,Terada, Tadafumi,Oshida, Jun-ichi,Morisaki, Masuo,Ikekawa, Nobuo
, p. 85 - 92 (2007/10/02)
To clarify the physiological significance of C-24 hydroxylation in vitamin D3 metabolism , vitamin D3 compounds blocked at C-24 by fluorine substituents, namely 24,24-difluoro-25-hydroxyvitamin D3 (1) and 24ξ-fluoro-25-hydroxyvitamin D3 (2) have been synthesized from 3β-hydroxychol-5-en-24-oic acid (13).
