7741-47-1

Basic information

• Product Name: 2-(3,4-dimethoxyphenyl)-3,5,7,8-tetramethoxy-4H-chromen-4-one
• Synonyms: 2-(3,4-Dimethoxyphenyl)-3,5,7,8-tetramethoxy-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3,5,7,8-tetramethoxy-
• CAS NO: 7741-47-1
• Molecular Formula: C₂₁H₂₂O₈
• Molecular Weight: 402.3946
• Mol File: 7741-47-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 598.2°C at 760 mmHg
• Flash Point: 261°C
• Density: 1.3g/cm³
• Vapor Pressure: 2.85E-14mmHg at 25°C
• Refractive Index: 1.581
• CAS DataBase Reference: 2-(3,4-dimethoxyphenyl)-3,5,7,8-tetramethoxy-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-dimethoxyphenyl)-3,5,7,8-tetramethoxy-4H-chromen-4-one(7741-47-1)
• EPA Substance Registry System: 2-(3,4-dimethoxyphenyl)-3,5,7,8-tetramethoxy-4H-chromen-4-one(7741-47-1)

Safety Data

• Hazardous Substances Data: 7741-47-1(Hazardous Substances Data)

Upstream product

• 489-35-0 gossypetin 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 14965-08-3 5,7,4'-trihydroxy-3,8,3'-trimethoxyflavone 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 1247-97-8 pentamethyl quercetin 
• 1245-15-4 retusin 
• 1244-78-6 2-(3,4-dimethoxyphenyl)-3-hydroxy-5,7-dimethoxy-4H-4-chromenone 
• 855-97-0 2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one 
• 29080-58-8 5-hydroxy-3',4',7-trimethoxyflavone 
• 76650-20-9 1-(2,4,6-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)propenone 
• 114021-60-2 2'-hydroxy-3,4,4',6'-tetramethoxychalcone 
• 7380-44-1 5,8-dihydroxy-3,7-dimethoxy-2-(3,4-dimethoxyphenyl)-4-benzopyrone 
• 14965-12-9 2-(3,4-dimethoxy-phenyl)-5-hydroxy-3,7,8-trimethoxy-chromen-4-one 

Downstream Products

• 93-07-2 Veratric acid 
• 14965-12-9 2-(3,4-dimethoxy-phenyl)-5-hydroxy-3,7,8-trimethoxy-chromen-4-one 
• 57528-78-6 limocitrin 3,7,4'-trimethyl ether-5-acetate 
• 72620-07-6 3,5-dihydroxy-7,8,3',4'-tetramethoxyflavone 

Relevant articles and documents

Regioselective hydroxylation of 2-hydroxychalcones by dimethyldioxirane towards polymethoxylated flavonoids

The flavone nucleus is part of a large number of natural products and medicinal compounds. In this presentation the novel regioselective hydroxylation of hydroxyarenes with DMD is described. The results showed further that flavonoids with 5-hydroxy group were selectively oxyfunctionalized at the para-position C8 carbon atom by DMD. Finally, according to this methodology, the naturally occurring isosinensetin, tangeretin, sinensetin, nobiletin, natsudaidain, gardenin B, 3,3′,4′,5,6,7,8- heptamethoxyflavone, quercetin and its derivatives were synthesized.

Taste modifier and a method of modifying taste

Taste modifier comprising a flavone derivative as an active ingredient of the general formula (I): STR1 wherein R1, R3, R4, R6 and R8 are independently a methoxy group or an hydrogen atom, R2 and R7 are methoxy groups, and R5 is a methoxy group or an hydroxy group, and a method of modifying taste, comprising adding a taste-modifying effective amount of the flavone derivative (I) to a product used in a mouth or an orally ingestible product. Various factors associated with taste can be modified, for example, the derivative can enhance sourness, reduce saltiness, inhibit unpleasant lasting of sweetness, enhance refreshing flavor and its continuity, reduce flavor associated with acetic acid, and enhance body, deliciousness and savor associated with the combination of these tastes.

ALKALOIDS, COUMARINS AND FLAVONOIDS OF MICROMELUM ZEYLANICUM

The leaves and stems of Micromelum zeylanicum have yielded a new oxazole alkaloid, O-methylhalfordinol, the coumarin micromelin and a flavone, 5-hydroxy-3,3',4',7,8-pentamethoxyflavone.In addition, the stems contained 6-formyl-7-methoxycoumarin, and the leaves contained the carbazole alkaloid koenigine and β-sitosterol.Chemical and spectral evidence are presented to support the proposed structures. - Key Word Index - Micromelum zeylanicum; Rutaceae; leaves; stems; oxazole; carbazole; coumarin; flavone; O-methylhalfordinol; koenigine; micromelin; 6-formyl-7-methoxycoumarin; 5-hydroxy-3,3',4',7,8-pentamethoxyflavone; β-sitosterol.